Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapy

Early diagnosis and timely rational therapy of DP allow to prevent disability, increase duration and improve the quality of life of patients with diabetes mellitus (DM). The most feasible practical diagnostic algorithm for DP is still a matter of debate. The article focuses on the most common form o...

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Main Authors: V. A. Golovacheva, V. A. Parfyonov
Format: Article
Language:Russian
Published: Remedium Group LLC 2015-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/447
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author V. A. Golovacheva
V. A. Parfyonov
author_facet V. A. Golovacheva
V. A. Parfyonov
author_sort V. A. Golovacheva
collection DOAJ
description Early diagnosis and timely rational therapy of DP allow to prevent disability, increase duration and improve the quality of life of patients with diabetes mellitus (DM). The most feasible practical diagnostic algorithm for DP is still a matter of debate. The article focuses on the most common form of DP - diabetic distal symmetrical sensorimotor polyneuropathy (DSSP). Effective non-pharmaceutical methods to improve the course of DP and DSSP include optimum control of blood glucose level, educational programs, lifestyle (diet, maintaining or achieving a healthy weight, therapeutic exercises, maintaining everyday activity) and, when indicated, cognitive-behavioral therapy. Symptomatic treatment of neuropathic pain in DSSP achieved significant success, however it fails to inhibit the damage to the peripheral nerves. The search for therapies aimed at changing the course of DSSP continues. In Russia, alpha-lipoic acid and vitamin B complex are discussed as possible pathogenetic treatments of DSSP. Cocarnit is a combination medicine containing vitamins B and metabolically active substances. Prospects for the use of the drug in the treatment of patients with DSSP are considered.
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spelling doaj.art-83e3d665a6d843c98db7ec5b4ca5cb862023-04-23T06:56:40ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902015-12-01018242910.21518/2079-701X-2015-18-24-29447Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapyV. A. Golovacheva0V. A. Parfyonov1First Moscow State Medical University named after I.M. SechenovFirst Moscow State Medical University named after I.M. SechenovEarly diagnosis and timely rational therapy of DP allow to prevent disability, increase duration and improve the quality of life of patients with diabetes mellitus (DM). The most feasible practical diagnostic algorithm for DP is still a matter of debate. The article focuses on the most common form of DP - diabetic distal symmetrical sensorimotor polyneuropathy (DSSP). Effective non-pharmaceutical methods to improve the course of DP and DSSP include optimum control of blood glucose level, educational programs, lifestyle (diet, maintaining or achieving a healthy weight, therapeutic exercises, maintaining everyday activity) and, when indicated, cognitive-behavioral therapy. Symptomatic treatment of neuropathic pain in DSSP achieved significant success, however it fails to inhibit the damage to the peripheral nerves. The search for therapies aimed at changing the course of DSSP continues. In Russia, alpha-lipoic acid and vitamin B complex are discussed as possible pathogenetic treatments of DSSP. Cocarnit is a combination medicine containing vitamins B and metabolically active substances. Prospects for the use of the drug in the treatment of patients with DSSP are considered.https://www.med-sovet.pro/jour/article/view/447диабетическая полиневропатияболевая диабетическая полиневропатиядиагностикалечениекогнитивно-поведенческая терапиякокарнитdiabetic polyneuropathypainful diabetic polyneuropathydiagnosistreatmentcognitive-behavioral therapycocarnit
spellingShingle V. A. Golovacheva
V. A. Parfyonov
Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapy
Медицинский совет
диабетическая полиневропатия
болевая диабетическая полиневропатия
диагностика
лечение
когнитивно-поведенческая терапия
кокарнит
diabetic polyneuropathy
painful diabetic polyneuropathy
diagnosis
treatment
cognitive-behavioral therapy
cocarnit
title Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapy
title_full Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapy
title_fullStr Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapy
title_full_unstemmed Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapy
title_short Management of patients with diabetic polyneuropathy: current guidelines for diagnosis and treatment, prospects for pharmacotherapy
title_sort management of patients with diabetic polyneuropathy current guidelines for diagnosis and treatment prospects for pharmacotherapy
topic диабетическая полиневропатия
болевая диабетическая полиневропатия
диагностика
лечение
когнитивно-поведенческая терапия
кокарнит
diabetic polyneuropathy
painful diabetic polyneuropathy
diagnosis
treatment
cognitive-behavioral therapy
cocarnit
url https://www.med-sovet.pro/jour/article/view/447
work_keys_str_mv AT vagolovacheva managementofpatientswithdiabeticpolyneuropathycurrentguidelinesfordiagnosisandtreatmentprospectsforpharmacotherapy
AT vaparfyonov managementofpatientswithdiabeticpolyneuropathycurrentguidelinesfordiagnosisandtreatmentprospectsforpharmacotherapy