Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia
Thyroid involvement is a common condition that can be recorded during the natural course of different systemic rheumatic diseases, including the mixed cryoglobulinemia (MC) syndrome or cryoglobulinemic vasculitis. MC is triggered by hepatitis C virus (HCV) chronic infection in the majority of cases;...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-07-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fendo.2017.00159/full |
| _version_ | 1828159628467240960 |
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| author | Clodoveo Ferri Michele Colaci Poupak Fallahi Silvia Martina Ferrari Alessandro Antonelli Dilia Giuggioli |
| author_facet | Clodoveo Ferri Michele Colaci Poupak Fallahi Silvia Martina Ferrari Alessandro Antonelli Dilia Giuggioli |
| author_sort | Clodoveo Ferri |
| collection | DOAJ |
| description | Thyroid involvement is a common condition that can be recorded during the natural course of different systemic rheumatic diseases, including the mixed cryoglobulinemia (MC) syndrome or cryoglobulinemic vasculitis. MC is triggered by hepatitis C virus (HCV) chronic infection in the majority of cases; it represents the prototype of autoimmune-lymphoproliferative disorders complicating a significant proportion of patients with chronic HCV infection. HCV is both hepato- and lymphotropic virus responsible for a great number of autoimmune/lymphoproliferative and/or neoplastic disorders. The complex of HCV-related hepatic and extrahepatic manifestations, including MC and thyroid involvement, may be termed “HCV syndrome.” Here, we describe the prevalence and clinico-serological characteristics of thyroid involvement, mainly autoimmune thyroiditis and papillary thyroid cancer, in patients with HCV syndrome with or without cryoglobulinemic vasculitis. |
| first_indexed | 2024-04-12T00:05:03Z |
| format | Article |
| id | doaj.art-83e749cd033f4adf8af3df296e3b13af |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-12T00:05:03Z |
| publishDate | 2017-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-83e749cd033f4adf8af3df296e3b13af2022-12-22T03:56:08ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922017-07-01810.3389/fendo.2017.00159278732Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed CryoglobulinemiaClodoveo Ferri0Michele Colaci1Poupak Fallahi2Silvia Martina Ferrari3Alessandro Antonelli4Dilia Giuggioli5Chair and Rheumatology Unit, Azienda Ospedaliero-Universitaria di Modena, Medical School, University of Modena and Reggio Emilia, Modena, ItalyChair and Rheumatology Unit, Azienda Ospedaliero-Universitaria di Modena, Medical School, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, ItalyDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, ItalyChair and Rheumatology Unit, Azienda Ospedaliero-Universitaria di Modena, Medical School, University of Modena and Reggio Emilia, Modena, ItalyThyroid involvement is a common condition that can be recorded during the natural course of different systemic rheumatic diseases, including the mixed cryoglobulinemia (MC) syndrome or cryoglobulinemic vasculitis. MC is triggered by hepatitis C virus (HCV) chronic infection in the majority of cases; it represents the prototype of autoimmune-lymphoproliferative disorders complicating a significant proportion of patients with chronic HCV infection. HCV is both hepato- and lymphotropic virus responsible for a great number of autoimmune/lymphoproliferative and/or neoplastic disorders. The complex of HCV-related hepatic and extrahepatic manifestations, including MC and thyroid involvement, may be termed “HCV syndrome.” Here, we describe the prevalence and clinico-serological characteristics of thyroid involvement, mainly autoimmune thyroiditis and papillary thyroid cancer, in patients with HCV syndrome with or without cryoglobulinemic vasculitis.http://journal.frontiersin.org/article/10.3389/fendo.2017.00159/fullhepatitis C virusthyroidautoimmune thyroiditisautoimmunitycryoglobulinemiacryoglobulinemic vasculitis |
| spellingShingle | Clodoveo Ferri Michele Colaci Poupak Fallahi Silvia Martina Ferrari Alessandro Antonelli Dilia Giuggioli Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia Frontiers in Endocrinology hepatitis C virus thyroid autoimmune thyroiditis autoimmunity cryoglobulinemia cryoglobulinemic vasculitis |
| title | Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia |
| title_full | Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia |
| title_fullStr | Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia |
| title_full_unstemmed | Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia |
| title_short | Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia |
| title_sort | thyroid involvement in hepatitis c virus infected patients with without mixed cryoglobulinemia |
| topic | hepatitis C virus thyroid autoimmune thyroiditis autoimmunity cryoglobulinemia cryoglobulinemic vasculitis |
| url | http://journal.frontiersin.org/article/10.3389/fendo.2017.00159/full |
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