PI3K signaling and Stat92E converge to modulate glial responsiveness to axonal injury.
Glial cells are exquisitely sensitive to neuronal injury but mechanisms by which glia establish competence to respond to injury, continuously gauge neuronal health, and rapidly activate reactive responses remain poorly defined. Here, we show glial PI3K signaling in the uninjured brain regulates base...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-11-01
|
| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC4219656?pdf=render |