IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESIS
Abstract. We have performed clinical and immunological investigation in the patients with trauma of face bones before and after stable mandibular ostheosynthesis. Blood samples for analysis were taken upon admission of the patient to clinics, and following treatment (3, 10, and 1-2 months). The pati...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/194 |
| _version_ | 1797198098238275584 |
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| author | O. V. Berdugina |
| author_facet | O. V. Berdugina |
| author_sort | O. V. Berdugina |
| collection | DOAJ |
| description | Abstract. We have performed clinical and immunological investigation in the patients with trauma of face bones before and after stable mandibular ostheosynthesis. Blood samples for analysis were taken upon admission of the patient to clinics, and following treatment (3, 10, and 1-2 months). The patients with initially retarded bone consolidation exhibited low levels of monocytes and lactoferrine before surgical treatment. It was shown that the consecutive stages of bone regeneration (inflammation, osteoblastic proliferation, collagenogenesis, and ossification) are accompanied by certain changes in immune parameters. In particular, we observed increased levels of IgМ, TNF, and activation of leucopoiesis after treatment. The results obtained allow us of discriminating some natural reactions of immune system in cases of normal and retarded bone consolidation. For each of these criteria, diagnostic sensitivity and informativity of tests are calculated, thus providing an opportunity to predict retarded consolidation in surgical treatment of the face bones. (Med. Immunol., 2007, vol. 10, N 4-5, pp 371-388). |
| first_indexed | 2024-03-08T05:51:44Z |
| format | Article |
| id | doaj.art-83e8aabf881f4b73a93c9cee967ab8c3 |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:54:27Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-83e8aabf881f4b73a93c9cee967ab8c32024-04-22T13:07:34ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-01104-537137810.15789/1563-0625-2008-4-5-371-378191IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESISO. V. Berdugina0ГОУ ВПО Уральская государственная медицинская академия Росздрава; ГУЗ «Свердловская областная клиническая больница № 1» МЗ СО, г. ЕкатеринбургAbstract. We have performed clinical and immunological investigation in the patients with trauma of face bones before and after stable mandibular ostheosynthesis. Blood samples for analysis were taken upon admission of the patient to clinics, and following treatment (3, 10, and 1-2 months). The patients with initially retarded bone consolidation exhibited low levels of monocytes and lactoferrine before surgical treatment. It was shown that the consecutive stages of bone regeneration (inflammation, osteoblastic proliferation, collagenogenesis, and ossification) are accompanied by certain changes in immune parameters. In particular, we observed increased levels of IgМ, TNF, and activation of leucopoiesis after treatment. The results obtained allow us of discriminating some natural reactions of immune system in cases of normal and retarded bone consolidation. For each of these criteria, diagnostic sensitivity and informativity of tests are calculated, thus providing an opportunity to predict retarded consolidation in surgical treatment of the face bones. (Med. Immunol., 2007, vol. 10, N 4-5, pp 371-388).https://www.mimmun.ru/mimmun/article/view/194immunological monitoringostheogenesis |
| spellingShingle | O. V. Berdugina IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESIS Медицинская иммунология immunological monitoring ostheogenesis |
| title | IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESIS |
| title_full | IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESIS |
| title_fullStr | IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESIS |
| title_full_unstemmed | IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESIS |
| title_short | IMMUNOLOGICAL MONITORING OF SLOW DOWN OSTHEOGENESIS |
| title_sort | immunological monitoring of slow down ostheogenesis |
| topic | immunological monitoring ostheogenesis |
| url | https://www.mimmun.ru/mimmun/article/view/194 |
| work_keys_str_mv | AT ovberdugina immunologicalmonitoringofslowdownostheogenesis |