The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis
Introduction. Urolithiasis is a multifactorial recurrent disease, unevenly spread throughout the world and characterizedby the formation of urinary stones of various chemical compositions, depending on pathogenesis, etiological, and epidemiological risk factors. Understanding the composition of chem...
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| Format: | Article |
| Language: | Russian |
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2021-10-01
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| Series: | Vestnik Urologii |
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| Online Access: | https://www.urovest.ru/jour/article/view/472 |
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| author | D. G. Lebedev V. I. Smirnova S. V. Lapin O. O. Burlaka E. V. Rozengauz V. L. Emanuel |
| author_facet | D. G. Lebedev V. I. Smirnova S. V. Lapin O. O. Burlaka E. V. Rozengauz V. L. Emanuel |
| author_sort | D. G. Lebedev |
| collection | DOAJ |
| description | Introduction. Urolithiasis is a multifactorial recurrent disease, unevenly spread throughout the world and characterizedby the formation of urinary stones of various chemical compositions, depending on pathogenesis, etiological, and epidemiological risk factors. Understanding the composition of chemicals and their prevailing ratios can help make decisions about treatment tactics, preventive measures to reduce the risk of recurrence and the prevalence of urolithiasis.Purpose of the study. To assess the distribution of chemical components in urinary stones along with an analysis of their population significance.Materials and methods. The urinary stones were obtained from 2854 patients with urolithiasis. The composition of urinary stones was analyzed by using an infrared spectroscopy method.Results. The predominance of oxalate stones was determined in multicomponent kidney stones (83,7%) and the prevalence of urate stones (54,2%) was revealed in monocomponent kidney stones. Urinary stones with a predominance of oxalates contained significantly fewer impurities (12.4%) than urinary stones with a predominance of urates, phosphates and carbonates with an average amount of impurities >24.0%.Conclusion. The analysis of urinary stones distribution based on pathogenic factors showed that the calcium metabolism disturbances prevail in the population of the Russian Federation (88.0%). |
| first_indexed | 2024-03-07T14:23:22Z |
| format | Article |
| id | doaj.art-83ea79da79e740a39d378da47eb6b4a7 |
| institution | Directory Open Access Journal |
| issn | 2308-6424 |
| language | Russian |
| last_indexed | 2024-03-07T14:23:22Z |
| publishDate | 2021-10-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Vestnik Urologii |
| spelling | doaj.art-83ea79da79e740a39d378da47eb6b4a72024-03-06T08:56:05ZrusState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationVestnik Urologii2308-64242021-10-0193445110.21886/2308-6424-2021-9-3-44-51328The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesisD. G. Lebedev0V. I. Smirnova1S. V. Lapin2O. O. Burlaka3E. V. Rozengauz4V. L. Emanuel5St. Petersburg Alexander City HospitalPavlov First St. Petersburg State Medical UniversityPavlov First St. Petersburg State Medical UniversitySt. Petersburg Alexander City Hospital; Mechnikov North-Western State Medical UniversityMechnikov North-Western State Medical University; Granov Russian Scientific Center for Radiology and Surgical TechnologiesPavlov First St. Petersburg State Medical UniversityIntroduction. Urolithiasis is a multifactorial recurrent disease, unevenly spread throughout the world and characterizedby the formation of urinary stones of various chemical compositions, depending on pathogenesis, etiological, and epidemiological risk factors. Understanding the composition of chemicals and their prevailing ratios can help make decisions about treatment tactics, preventive measures to reduce the risk of recurrence and the prevalence of urolithiasis.Purpose of the study. To assess the distribution of chemical components in urinary stones along with an analysis of their population significance.Materials and methods. The urinary stones were obtained from 2854 patients with urolithiasis. The composition of urinary stones was analyzed by using an infrared spectroscopy method.Results. The predominance of oxalate stones was determined in multicomponent kidney stones (83,7%) and the prevalence of urate stones (54,2%) was revealed in monocomponent kidney stones. Urinary stones with a predominance of oxalates contained significantly fewer impurities (12.4%) than urinary stones with a predominance of urates, phosphates and carbonates with an average amount of impurities >24.0%.Conclusion. The analysis of urinary stones distribution based on pathogenic factors showed that the calcium metabolism disturbances prevail in the population of the Russian Federation (88.0%).https://www.urovest.ru/jour/article/view/472urolithiasisinfrared spectroscopychemical compositionurinary stonescalcium metabolism disturbances |
| spellingShingle | D. G. Lebedev V. I. Smirnova S. V. Lapin O. O. Burlaka E. V. Rozengauz V. L. Emanuel The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis Vestnik Urologii urolithiasis infrared spectroscopy chemical composition urinary stones calcium metabolism disturbances |
| title | The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis |
| title_full | The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis |
| title_fullStr | The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis |
| title_full_unstemmed | The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis |
| title_short | The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis |
| title_sort | value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis |
| topic | urolithiasis infrared spectroscopy chemical composition urinary stones calcium metabolism disturbances |
| url | https://www.urovest.ru/jour/article/view/472 |
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