Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer

Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer

Low response rate and recurrence are common issues in lung cancer; thus, identifying a potential compound for these patients is essential. Utilizing an in silico screening method, we identified withaferin A (WA), a cell-permeable steroidal lactone initially extracted from <i>Withania somnifera...

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Bibliographic Details
Main Authors: Jade H.-M. Hsu, Peter M.-H. Chang, Tai-Shan Cheng, Yu-Lun Kuo, Alexander T.-H. Wu, Thu-Ha Tran, Yun-Hsuan Yang, Jing-Ming Chen, Yu-Chen Tsai, Yeh-Shiu Chu, Tse- Hung Huang, Chi-Ying F. Huang, Jin-Mei Lai
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
non-small-cell lung cancer
withaferin A
connectivity map
synergistic effect
Online Access:https://www.mdpi.com/2072-6694/11/7/1003

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