Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis.

Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis.

Pregnane X Receptor (PXR), a master regulator of drug metabolism and inflammation, is abundantly expressed in the gastrointestinal tract. Baicalein and its O-glucuronide baicalin are potent anti-inflammatory and anti-cancer herbal flavonoids that undergo a complex cycle of interconversion in the liv...

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Bibliographic Details
Main Authors: Wei Dou, Subhajit Mukherjee, Hao Li, Madhukumar Venkatesh, Hongwei Wang, Sandhya Kortagere, Ariel Peleg, Sridhar S Chilimuri, Zheng-Tao Wang, Ying Feng, Eric R Fearon, Sridhar Mani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398007?pdf=render

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http://europepmc.org/articles/PMC3398007?pdf=render

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