KTN1 Variants Underlying Putamen Gray Matter Volumes and Parkinson’s Disease

KTN1 Variants Underlying Putamen Gray Matter Volumes and Parkinson’s Disease

BackgroundSelective loss of dopaminergic neurons and diminished putamen gray matter volume (GMV) represents a central feature of Parkinson’s disease (PD). Recent studies have reported specific effects of kinectin 1 gene (KTN1) variants on the putamen GMV.ObjectiveTo examine the relationship of KTN1...

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Bibliographic Details
Main Authors: Qiao Mao, Xiaoping Wang, Bin Chen, Longhua Fan, Shuhong Wang, Yong Zhang, Xiandong Lin, Yuping Cao, Yun-Cheng Wu, Jiawu Ji, Jianying Xu, Jianming Zheng, Huihao Zhang, Chengchou Zheng, Wenzhong Chen, Wenhong Cheng, Xingqun Luo, Kesheng Wang, Lingjun Zuo, Longli Kang, Chiang-Shan R. Li, Xingguang Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson’s disease
KTN1
putamen
substantia nigra
gray matter volume
mRNA expression
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00651/full

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