Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement
It is known that research of immune system using separate parameters doesn't allow to estimate it as one. The aim of the work was to find new approaches to the estimation of immune system state for the determination of character and intensity of immunopathological manifestations in patients wit...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2015-11-01
|
| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/133 |
| _version_ | 1797237414924648448 |
|---|---|
| author | L. A. Dmitrieva V. F. Lebedev S. N. Leonova |
| author_facet | L. A. Dmitrieva V. F. Lebedev S. N. Leonova |
| author_sort | L. A. Dmitrieva |
| collection | DOAJ |
| description | It is known that research of immune system using separate parameters doesn't allow to estimate it as one. The aim of the work was to find new approaches to the estimation of immune system state for the determination of character and intensity of immunopathological manifestations in patients with hip joint pathology. We examined immune status in 73 patients with degenerative-dystrophic injuries and in 18 patients with posttraumatic hip joint injuries. We found the most significant immunological indices that allow to determine the state of immune reactivity of the patient before the operation. We identified two groups of patients: with presumably "compensated" and "subcompensated" form of immunodeficient state. It was shown that infectious infectious complications in the area of endoprosthesis appear in patients with low immune reactivity on the basis of calculation of equations of linear function in patients with posttraumatic coxarthrosis. The results of the research showed that it's not necessary to analyze many immunological indices to estimate the state of immune reactivity of an organism. Using discriminant analysis allows to reveal the determinant factors that characterize distinctness of Junctional state of immune system of a certain patient and to determine the risk of development of postoperative complications. |
| first_indexed | 2024-03-08T12:19:01Z |
| format | Article |
| id | doaj.art-84012b7fe8d14bbc803d1d1f7b55dacf |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:19:23Z |
| publishDate | 2015-11-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-84012b7fe8d14bbc803d1d1f7b55dacf2024-03-28T07:49:15ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962015-11-01062126133Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacementL. A. Dmitrieva0V. F. Lebedev1S. N. Leonova2Irkutsk Scientific Center of Surgery and TraumatologyIrkutsk State Medical UniversityIrkutsk Scientific Center of Surgery and TraumatologyIt is known that research of immune system using separate parameters doesn't allow to estimate it as one. The aim of the work was to find new approaches to the estimation of immune system state for the determination of character and intensity of immunopathological manifestations in patients with hip joint pathology. We examined immune status in 73 patients with degenerative-dystrophic injuries and in 18 patients with posttraumatic hip joint injuries. We found the most significant immunological indices that allow to determine the state of immune reactivity of the patient before the operation. We identified two groups of patients: with presumably "compensated" and "subcompensated" form of immunodeficient state. It was shown that infectious infectious complications in the area of endoprosthesis appear in patients with low immune reactivity on the basis of calculation of equations of linear function in patients with posttraumatic coxarthrosis. The results of the research showed that it's not necessary to analyze many immunological indices to estimate the state of immune reactivity of an organism. Using discriminant analysis allows to reveal the determinant factors that characterize distinctness of Junctional state of immune system of a certain patient and to determine the risk of development of postoperative complications.https://www.actabiomedica.ru/jour/article/view/133immunologic reactivitycoxarthrosispredictionendoprosthesis replacement |
| spellingShingle | L. A. Dmitrieva V. F. Lebedev S. N. Leonova Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement Acta Biomedica Scientifica immunologic reactivity coxarthrosis prediction endoprosthesis replacement |
| title | Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement |
| title_full | Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement |
| title_fullStr | Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement |
| title_full_unstemmed | Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement |
| title_short | Immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement |
| title_sort | immunologic reactivity of an organism in patients with coxarthrosis in the assessment of risk of development of postoperative complications at the endoprosthesis replacement |
| topic | immunologic reactivity coxarthrosis prediction endoprosthesis replacement |
| url | https://www.actabiomedica.ru/jour/article/view/133 |
| work_keys_str_mv | AT ladmitrieva immunologicreactivityofanorganisminpatientswithcoxarthrosisintheassessmentofriskofdevelopmentofpostoperativecomplicationsattheendoprosthesisreplacement AT vflebedev immunologicreactivityofanorganisminpatientswithcoxarthrosisintheassessmentofriskofdevelopmentofpostoperativecomplicationsattheendoprosthesisreplacement AT snleonova immunologicreactivityofanorganisminpatientswithcoxarthrosisintheassessmentofriskofdevelopmentofpostoperativecomplicationsattheendoprosthesisreplacement |