Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Abstract The aim of the study was to determine the antioxidant activity and assess the lipophilicity and skin penetration of eugenyl chloroacetate (EChA), eugenyl dichloroacetate (EDChA), and eugenyl trichloroacetate (ETChA). Identification of the obtained products was based on gas chromatography (G...

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Bibliographic Details
Main Authors: Edyta Makuch, Anna Nowak, Andrzej Günther, Robert Pełech, Łukasz Kucharski, Wiktoria Duchnik, Adam Klimowicz
Format: Article
Language:English
Published: SpringerOpen 2020-10-01
Series:AMB Express
Subjects:
Eugenol
New esters of eugenol
log P
Skin penetration
Franz cell
Antioxidant activity
Online Access:http://link.springer.com/article/10.1186/s13568-020-01122-3

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