PTEN Hamartoma Tumor Syndrome and Immune Dysregulation

PTEN Hamartoma Tumor Syndrome and Immune Dysregulation

Carriers of a pathogenic germline mutations in the PTEN gene, a well-known tumor suppressor gene, are at increased risk of multiple benign and malignant tumors, e.g. breast, thyroid, endometrial and colon cancer. This is called PTEN Hamartomous Tumor Syndrome (PHTS). PHTS patients may also have an i...

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Bibliographic Details
Main Authors: Marc Eissing, Lise Ripken, Gerty Schreibelt, Harm Westdorp, Marjolijn Ligtenberg, Romana Netea-Maier, Mihai G. Netea, I. Jolanda M. de Vries, Nicoline Hoogerbrugge
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523318304704

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http://www.sciencedirect.com/science/article/pii/S1936523318304704

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