FYN: emerging biological roles and potential therapeutic targets in cancer
Abstract Src family protein kinases (SFKs) play a key role in cell adhesion, invasion, proliferation, survival, apoptosis, and angiogenesis during tumor development. In humans, SFKs consists of eight family members with similar structure and function. There is a high level of overexpression or hyper...
Main Authors: | SanFei Peng, Yang Fu |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
|
Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-023-03930-0 |
Similar Items
-
FYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancer
by: SanFei Peng, et al.
Published: (2023-04-01) -
FYN promotes gastric cancer metastasis by activating STAT3-mediated epithelial-mesenchymal transition
by: Jie Yu, et al.
Published: (2020-11-01) -
Data supporting the role of Fyn in embryonic sciatic nerve fasciculation
by: Tomohiro Torii, et al.
Published: (2017-04-01) -
Post-status epilepticus treatment with the Fyn inhibitor, saracatinib, improves cognitive function in mice
by: Xin-Ming Luo, et al.
Published: (2021-01-01) -
Chrysin alleviated CUMS-induced depressive-like behaviors in mice via directly targeting Fyn
by: Zhipeng Li, et al.
Published: (2023-07-01)