Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test

A case of a 12-year-old boy who developed catatonia is presented. He had no previous psychiatric history but has a family history of affective disorder. An extensive medical workup was negative. Despite a negative lorazepam challenge test, lorazepam was titrated up to 24 mg/day, with resolution of m...

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Main Authors: Laura Ridgeway, Albert Okoye, Ian McClelland, Dirk Dhossche, Deniz Kutay, Mario Loureiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.637886/full
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author Laura Ridgeway
Albert Okoye
Ian McClelland
Dirk Dhossche
Deniz Kutay
Mario Loureiro
author_facet Laura Ridgeway
Albert Okoye
Ian McClelland
Dirk Dhossche
Deniz Kutay
Mario Loureiro
author_sort Laura Ridgeway
collection DOAJ
description A case of a 12-year-old boy who developed catatonia is presented. He had no previous psychiatric history but has a family history of affective disorder. An extensive medical workup was negative. Despite a negative lorazepam challenge test, lorazepam was titrated up to 24 mg/day, with resolution of most catatonic symptoms. The case highlights an important point in the management of catatonia that may be a source of confusion, i.e., a positive lorazepam challenge test corroborates the diagnosis of catatonia; however, a negative lorazepam challenge test does not negate the diagnosis of catatonia, and subsequent focused benzodiazepine treatment may still be effective.
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spelling doaj.art-840875081d404a019680473d1e0ef19a2022-12-21T23:23:16ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402021-03-011210.3389/fpsyt.2021.637886637886Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge TestLaura Ridgeway0Albert Okoye1Ian McClelland2Dirk Dhossche3Deniz Kutay4Mario Loureiro5Department of Child and Adolescent Psychiatry, University Hospital Waterford, Waterford, IrelandDepartment of Child and Adolescent Psychiatry, University Hospital Waterford, Waterford, IrelandDepartment of Liaison Psychiatry, Children's University Hospital, Dublin, IrelandDepartment of Psychiatry and Human Behaviour, University of Mississippi Medical Center, Jackson, MS, United StatesDepartment of Child and Adolescent Psychiatry, University Hospital Waterford, Waterford, IrelandDepartment of Child and Adolescent Psychiatry, University Hospital Waterford, Waterford, IrelandA case of a 12-year-old boy who developed catatonia is presented. He had no previous psychiatric history but has a family history of affective disorder. An extensive medical workup was negative. Despite a negative lorazepam challenge test, lorazepam was titrated up to 24 mg/day, with resolution of most catatonic symptoms. The case highlights an important point in the management of catatonia that may be a source of confusion, i.e., a positive lorazepam challenge test corroborates the diagnosis of catatonia; however, a negative lorazepam challenge test does not negate the diagnosis of catatonia, and subsequent focused benzodiazepine treatment may still be effective.https://www.frontiersin.org/articles/10.3389/fpsyt.2021.637886/fullcatatoniapaediatricdepressionlorazepamcatatonia behaviorchild
spellingShingle Laura Ridgeway
Albert Okoye
Ian McClelland
Dirk Dhossche
Deniz Kutay
Mario Loureiro
Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test
Frontiers in Psychiatry
catatonia
paediatric
depression
lorazepam
catatonia behavior
child
title Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test
title_full Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test
title_fullStr Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test
title_full_unstemmed Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test
title_short Case Report: A Case of Pediatric Catatonia: Role of the Lorazepam Challenge Test
title_sort case report a case of pediatric catatonia role of the lorazepam challenge test
topic catatonia
paediatric
depression
lorazepam
catatonia behavior
child
url https://www.frontiersin.org/articles/10.3389/fpsyt.2021.637886/full
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