Irisin Enhances Mitochondrial Function in Osteoclast Progenitors during Differentiation

Irisin Enhances Mitochondrial Function in Osteoclast Progenitors during Differentiation

Irisin is a myokine released from muscle during exercise with distinct signaling effects on tissues throughout the body, including an influence on skeletal remodeling. Our previous work has shown that irisin stimulates resorption, a key first step in bone remodeling, by enhancing osteoclastogenesis....

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Bibliographic Details
Main Authors: Eben Estell, Tsunagu Ichikawa, Paige Giffault, Lynda Bonewald, Bruce Spiegelman, Clifford Rosen
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomedicines
Subjects:
irisin
osteoclast
osteoclast progenitor
mitochondria
oxidative respiration
Online Access:https://www.mdpi.com/2227-9059/11/12/3311

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