Utility of the succinate:fumarate ratio for assessing SDH dysfunction in different tumor types

Utility of the succinate:fumarate ratio for assessing SDH dysfunction in different tumor types

Objective: Mutations of genes encoding the four subunits of succinate dehydrogenase (SDH) have been associated with pheochromocytoma and paraganglioma (PPGLs), gastrointestinal stromal tumors (GISTs) and renal cell carcinomas (RCCs). These tumors have not been characterized in a way that reflects se...

书目详细资料
Main Authors:	Edward Kim, Michael JP. Wright, Loretta Sioson, Talia Novos, Anthony J. Gill, Diana E. Benn, Christopher White, Trisha Dwight, Roderick J. Clifton-Bligh
格式:	文件
语言:	English
出版:	Elsevier 2017-03-01
丛编:	Molecular Genetics and Metabolism Reports
主题:	Succinate dehydrogenase deficiency Mass spectrometry Pheochromocytoma and paraganglioma Gastrointestinal stromal tumor Renal cell carcinoma
在线阅读:	http://www.sciencedirect.com/science/article/pii/S2214426916301288

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