Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case report
Synchronous endometrial and ovarian carcinoma is a rare instance and it accounts for 50 to 70% of all synchronous female genital tract tumors. However, it is very rare to find synchronous endometrial carcinoma and ovarian sex cord–stromal tumor (thecoma). The present case is a 75-year-old woman with...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=2;spage=437;epage=439;aulast=Sethi |
| _version_ | 1818533563819098112 |
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| author | Neha Sethi Richa Sharma Nitin Khunteta Maneesh K Vijay Chetna Mehrol M L Yadav |
| author_facet | Neha Sethi Richa Sharma Nitin Khunteta Maneesh K Vijay Chetna Mehrol M L Yadav |
| author_sort | Neha Sethi |
| collection | DOAJ |
| description | Synchronous endometrial and ovarian carcinoma is a rare instance and it accounts for 50 to 70% of all synchronous female genital tract tumors. However, it is very rare to find synchronous endometrial carcinoma and ovarian sex cord–stromal tumor (thecoma). The present case is a 75-year-old woman with a complaint of post-menopausal vaginal bleeding. Radiologically, the magnetic resonance imaging (MRI) pelvis revealed altered signal intensity mass in the uterus. Frozen section and routine histopathological examination were done on radical hysterectomy. Microscopically, serous carcinoma involving uterine corpus and left Fallopian tube was identified along with the unusual finding of contralateral ovarian sex cord–stromal tumor (thecoma), which was confirmed on immunohistochemical examination. It is a very rare association and is first reported in the present study after a thorough search of the published literature. Their relationship based on a high level of estrogen produced by the hyperactive ovary is controversial as serous carcinomas are less hormone-dependent. |
| first_indexed | 2024-12-11T18:00:23Z |
| format | Article |
| id | doaj.art-8416bb7eda6f4cb7bc70afc828f2af63 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-11T18:00:23Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-8416bb7eda6f4cb7bc70afc828f2af632022-12-22T00:55:54ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292022-01-0165243743910.4103/IJPM.IJPM_1424_20Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case reportNeha SethiRicha SharmaNitin KhuntetaManeesh K VijayChetna MehrolM L YadavSynchronous endometrial and ovarian carcinoma is a rare instance and it accounts for 50 to 70% of all synchronous female genital tract tumors. However, it is very rare to find synchronous endometrial carcinoma and ovarian sex cord–stromal tumor (thecoma). The present case is a 75-year-old woman with a complaint of post-menopausal vaginal bleeding. Radiologically, the magnetic resonance imaging (MRI) pelvis revealed altered signal intensity mass in the uterus. Frozen section and routine histopathological examination were done on radical hysterectomy. Microscopically, serous carcinoma involving uterine corpus and left Fallopian tube was identified along with the unusual finding of contralateral ovarian sex cord–stromal tumor (thecoma), which was confirmed on immunohistochemical examination. It is a very rare association and is first reported in the present study after a thorough search of the published literature. Their relationship based on a high level of estrogen produced by the hyperactive ovary is controversial as serous carcinomas are less hormone-dependent.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=2;spage=437;epage=439;aulast=Sethiserous carcinomasex cord–stromal tumorsynchronous tumorsthecoma |
| spellingShingle | Neha Sethi Richa Sharma Nitin Khunteta Maneesh K Vijay Chetna Mehrol M L Yadav Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case report Indian Journal of Pathology and Microbiology serous carcinoma sex cord–stromal tumor synchronous tumors thecoma |
| title | Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case report |
| title_full | Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case report |
| title_fullStr | Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case report |
| title_full_unstemmed | Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case report |
| title_short | Synchronous uterine serous carcinoma and ovarian sex cord stromal tumor (thecoma)–A rare first case report |
| title_sort | synchronous uterine serous carcinoma and ovarian sex cord stromal tumor thecoma a rare first case report |
| topic | serous carcinoma sex cord–stromal tumor synchronous tumors thecoma |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=2;spage=437;epage=439;aulast=Sethi |
| work_keys_str_mv | AT nehasethi synchronousuterineserouscarcinomaandovariansexcordstromaltumorthecomaararefirstcasereport AT richasharma synchronousuterineserouscarcinomaandovariansexcordstromaltumorthecomaararefirstcasereport AT nitinkhunteta synchronousuterineserouscarcinomaandovariansexcordstromaltumorthecomaararefirstcasereport AT maneeshkvijay synchronousuterineserouscarcinomaandovariansexcordstromaltumorthecomaararefirstcasereport AT chetnamehrol synchronousuterineserouscarcinomaandovariansexcordstromaltumorthecomaararefirstcasereport AT mlyadav synchronousuterineserouscarcinomaandovariansexcordstromaltumorthecomaararefirstcasereport |