Quality of life in <i>Wilson′s disease</i>
<b>Background:</b> Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. <b> Aim:</b> To correlate clinical severity and QoL in patients with Wilson′s disease (WD). <b> Materials and Methods:</b>...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2008-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=1;spage=37;epage=40;aulast=Komal |
| _version_ | 1828531442903154688 |
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| author | Komal Kumar R Taly A Nair K.P.S Sinha S Prashanth L Vidya N Arunodaya G Rao S |
| author_facet | Komal Kumar R Taly A Nair K.P.S Sinha S Prashanth L Vidya N Arunodaya G Rao S |
| author_sort | Komal Kumar R |
| collection | DOAJ |
| description | <b>Background:</b> Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. <b> Aim:</b> To correlate clinical severity and QoL in patients with Wilson′s disease (WD). <b> Materials and Methods:</b> We evaluated patients of WD on regular follow up for at least two years and aged over 18 years using Neurological Symptom Score (NSS) for clinical severity and WHO-BREF for QoL at a university teaching hospital. Patients with inability to respond to the questionnaire due to behavioral problems, low IQ or other disease related factors were excluded. These 30 patients (M:F:: 23:7) had a mean age of 27.97 ± 11.16 years at evaluation and the mean duration of treatment of 9.2 ± 6.4 years. <b> Results:</b> All four domains of WHO-QoL-BREF viz., Physical, Psychological, Social and Environmental correlated well with each other (<i> p</i> < 0.01). The NSS correlated inversely with the physical domain (<i> p</i> < 0.02), while the duration of treatment had a positive correlation with the physical domain (<i> p</i> < 0.01). None of the other features of QoL showed any significant correlation with age, NSS or duration of treatment. <b> Conclusion:</b> QoL is complementary to formal neurological assessment and should be routinely incorporated in the evaluation of outcome of patients with WD and other chronic neurological disorders. |
| first_indexed | 2024-12-11T22:38:44Z |
| format | Article |
| id | doaj.art-8417531a0e07435f81432b42bda37f89 |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-12-11T22:38:44Z |
| publishDate | 2008-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-8417531a0e07435f81432b42bda37f892022-12-22T00:47:53ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492008-01-011113740Quality of life in <i>Wilson′s disease</i>Komal Kumar RTaly ANair K.P.SSinha SPrashanth LVidya NArunodaya GRao S<b>Background:</b> Assessment of Quality of life (QoL) is fast assuming significance as the measure of health in many disorders. <b> Aim:</b> To correlate clinical severity and QoL in patients with Wilson′s disease (WD). <b> Materials and Methods:</b> We evaluated patients of WD on regular follow up for at least two years and aged over 18 years using Neurological Symptom Score (NSS) for clinical severity and WHO-BREF for QoL at a university teaching hospital. Patients with inability to respond to the questionnaire due to behavioral problems, low IQ or other disease related factors were excluded. These 30 patients (M:F:: 23:7) had a mean age of 27.97 ± 11.16 years at evaluation and the mean duration of treatment of 9.2 ± 6.4 years. <b> Results:</b> All four domains of WHO-QoL-BREF viz., Physical, Psychological, Social and Environmental correlated well with each other (<i> p</i> < 0.01). The NSS correlated inversely with the physical domain (<i> p</i> < 0.02), while the duration of treatment had a positive correlation with the physical domain (<i> p</i> < 0.01). None of the other features of QoL showed any significant correlation with age, NSS or duration of treatment. <b> Conclusion:</b> QoL is complementary to formal neurological assessment and should be routinely incorporated in the evaluation of outcome of patients with WD and other chronic neurological disorders.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=1;spage=37;epage=40;aulast=KomalQuality of lifeWHO-BREFWilson′s disease |
| spellingShingle | Komal Kumar R Taly A Nair K.P.S Sinha S Prashanth L Vidya N Arunodaya G Rao S Quality of life in <i>Wilson′s disease</i> Annals of Indian Academy of Neurology Quality of life WHO-BREF Wilson′s disease |
| title | Quality of life in <i>Wilson′s disease</i> |
| title_full | Quality of life in <i>Wilson′s disease</i> |
| title_fullStr | Quality of life in <i>Wilson′s disease</i> |
| title_full_unstemmed | Quality of life in <i>Wilson′s disease</i> |
| title_short | Quality of life in <i>Wilson′s disease</i> |
| title_sort | quality of life in i wilson x2032 s disease i |
| topic | Quality of life WHO-BREF Wilson′s disease |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2008;volume=11;issue=1;spage=37;epage=40;aulast=Komal |
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