Hybrid Integrated Label-Free Chemical and Biological Sensors

Label-free sensors based on electrical, mechanical and optical transduction methods have potential applications in numerous areas of society, ranging from healthcare to environmental monitoring. Initial research in the field focused on the development and optimization of various sensor platforms fab...

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Main Authors: Simin Mehrabani, Ashley J. Maker, Andrea M. Armani
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/14/4/5890
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author Simin Mehrabani
Ashley J. Maker
Andrea M. Armani
author_facet Simin Mehrabani
Ashley J. Maker
Andrea M. Armani
author_sort Simin Mehrabani
collection DOAJ
description Label-free sensors based on electrical, mechanical and optical transduction methods have potential applications in numerous areas of society, ranging from healthcare to environmental monitoring. Initial research in the field focused on the development and optimization of various sensor platforms fabricated from a single material system, such as fiber-based optical sensors and silicon nanowire-based electrical sensors. However, more recent research efforts have explored designing sensors fabricated from multiple materials. For example, synthetic materials and/or biomaterials can also be added to the sensor to improve its response toward analytes of interest. By leveraging the properties of the different material systems, these hybrid sensing devices can have significantly improved performance over their single-material counterparts (better sensitivity, specificity, signal to noise, and/or detection limits). This review will briefly discuss some of the methods for creating these multi-material sensor platforms and the advances enabled by this design approach.
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spelling doaj.art-8419eb01601145479c384a823d18b9862022-12-22T04:22:55ZengMDPI AGSensors1424-82202014-03-011445890592810.3390/s140405890s140405890Hybrid Integrated Label-Free Chemical and Biological SensorsSimin Mehrabani0Ashley J. Maker1Andrea M. Armani2Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USAMork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USAMork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USALabel-free sensors based on electrical, mechanical and optical transduction methods have potential applications in numerous areas of society, ranging from healthcare to environmental monitoring. Initial research in the field focused on the development and optimization of various sensor platforms fabricated from a single material system, such as fiber-based optical sensors and silicon nanowire-based electrical sensors. However, more recent research efforts have explored designing sensors fabricated from multiple materials. For example, synthetic materials and/or biomaterials can also be added to the sensor to improve its response toward analytes of interest. By leveraging the properties of the different material systems, these hybrid sensing devices can have significantly improved performance over their single-material counterparts (better sensitivity, specificity, signal to noise, and/or detection limits). This review will briefly discuss some of the methods for creating these multi-material sensor platforms and the advances enabled by this design approach.http://www.mdpi.com/1424-8220/14/4/5890sensoractive materialschemical and biological detection
spellingShingle Simin Mehrabani
Ashley J. Maker
Andrea M. Armani
Hybrid Integrated Label-Free Chemical and Biological Sensors
Sensors
sensor
active materials
chemical and biological detection
title Hybrid Integrated Label-Free Chemical and Biological Sensors
title_full Hybrid Integrated Label-Free Chemical and Biological Sensors
title_fullStr Hybrid Integrated Label-Free Chemical and Biological Sensors
title_full_unstemmed Hybrid Integrated Label-Free Chemical and Biological Sensors
title_short Hybrid Integrated Label-Free Chemical and Biological Sensors
title_sort hybrid integrated label free chemical and biological sensors
topic sensor
active materials
chemical and biological detection
url http://www.mdpi.com/1424-8220/14/4/5890
work_keys_str_mv AT siminmehrabani hybridintegratedlabelfreechemicalandbiologicalsensors
AT ashleyjmaker hybridintegratedlabelfreechemicalandbiologicalsensors
AT andreamarmani hybridintegratedlabelfreechemicalandbiologicalsensors