Hybrid Integrated Label-Free Chemical and Biological Sensors
Label-free sensors based on electrical, mechanical and optical transduction methods have potential applications in numerous areas of society, ranging from healthcare to environmental monitoring. Initial research in the field focused on the development and optimization of various sensor platforms fab...
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Format: | Article |
Language: | English |
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MDPI AG
2014-03-01
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Series: | Sensors |
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Online Access: | http://www.mdpi.com/1424-8220/14/4/5890 |
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author | Simin Mehrabani Ashley J. Maker Andrea M. Armani |
author_facet | Simin Mehrabani Ashley J. Maker Andrea M. Armani |
author_sort | Simin Mehrabani |
collection | DOAJ |
description | Label-free sensors based on electrical, mechanical and optical transduction methods have potential applications in numerous areas of society, ranging from healthcare to environmental monitoring. Initial research in the field focused on the development and optimization of various sensor platforms fabricated from a single material system, such as fiber-based optical sensors and silicon nanowire-based electrical sensors. However, more recent research efforts have explored designing sensors fabricated from multiple materials. For example, synthetic materials and/or biomaterials can also be added to the sensor to improve its response toward analytes of interest. By leveraging the properties of the different material systems, these hybrid sensing devices can have significantly improved performance over their single-material counterparts (better sensitivity, specificity, signal to noise, and/or detection limits). This review will briefly discuss some of the methods for creating these multi-material sensor platforms and the advances enabled by this design approach. |
first_indexed | 2024-04-11T13:01:43Z |
format | Article |
id | doaj.art-8419eb01601145479c384a823d18b986 |
institution | Directory Open Access Journal |
issn | 1424-8220 |
language | English |
last_indexed | 2024-04-11T13:01:43Z |
publishDate | 2014-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Sensors |
spelling | doaj.art-8419eb01601145479c384a823d18b9862022-12-22T04:22:55ZengMDPI AGSensors1424-82202014-03-011445890592810.3390/s140405890s140405890Hybrid Integrated Label-Free Chemical and Biological SensorsSimin Mehrabani0Ashley J. Maker1Andrea M. Armani2Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USAMork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USAMork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USALabel-free sensors based on electrical, mechanical and optical transduction methods have potential applications in numerous areas of society, ranging from healthcare to environmental monitoring. Initial research in the field focused on the development and optimization of various sensor platforms fabricated from a single material system, such as fiber-based optical sensors and silicon nanowire-based electrical sensors. However, more recent research efforts have explored designing sensors fabricated from multiple materials. For example, synthetic materials and/or biomaterials can also be added to the sensor to improve its response toward analytes of interest. By leveraging the properties of the different material systems, these hybrid sensing devices can have significantly improved performance over their single-material counterparts (better sensitivity, specificity, signal to noise, and/or detection limits). This review will briefly discuss some of the methods for creating these multi-material sensor platforms and the advances enabled by this design approach.http://www.mdpi.com/1424-8220/14/4/5890sensoractive materialschemical and biological detection |
spellingShingle | Simin Mehrabani Ashley J. Maker Andrea M. Armani Hybrid Integrated Label-Free Chemical and Biological Sensors Sensors sensor active materials chemical and biological detection |
title | Hybrid Integrated Label-Free Chemical and Biological Sensors |
title_full | Hybrid Integrated Label-Free Chemical and Biological Sensors |
title_fullStr | Hybrid Integrated Label-Free Chemical and Biological Sensors |
title_full_unstemmed | Hybrid Integrated Label-Free Chemical and Biological Sensors |
title_short | Hybrid Integrated Label-Free Chemical and Biological Sensors |
title_sort | hybrid integrated label free chemical and biological sensors |
topic | sensor active materials chemical and biological detection |
url | http://www.mdpi.com/1424-8220/14/4/5890 |
work_keys_str_mv | AT siminmehrabani hybridintegratedlabelfreechemicalandbiologicalsensors AT ashleyjmaker hybridintegratedlabelfreechemicalandbiologicalsensors AT andreamarmani hybridintegratedlabelfreechemicalandbiologicalsensors |