Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles
The rate of monozygotic twinning (MZT) has seen a gradual increase in recent years. Numerous parameters involved in ART procedures are blamed for this surge, even though the exact explanation is as yet unknown. Our study’s objectives were to determine the risk variables for monozygotic twinning afte...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/7/2593 |
| _version_ | 1797607656653848576 |
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| author | Nikit Kadam George Woodhead Louise Kellam Alison Campbell Kanna Jayaprakasan |
| author_facet | Nikit Kadam George Woodhead Louise Kellam Alison Campbell Kanna Jayaprakasan |
| author_sort | Nikit Kadam |
| collection | DOAJ |
| description | The rate of monozygotic twinning (MZT) has seen a gradual increase in recent years. Numerous parameters involved in ART procedures are blamed for this surge, even though the exact explanation is as yet unknown. Our study’s objectives were to determine the risk variables for monozygotic twinning after ART and to estimate their prevalence. We examined 25,794 IVF cycles for the incidence of monozygotic twinning in this observational analysis. Our study, which was carried out across seven tertiary IVF centres over the course of four years, found an overall MZT rate of 0.37% per embryo transfer procedure and 0.88% of all pregnancies. Monozygotic twinning was more commonly seen in fresh single-embryo transfer (SET) and blastocyst transfer cycles. Larger multicentre studies are needed to explore the potential risk variables. |
| first_indexed | 2024-03-11T05:32:55Z |
| format | Article |
| id | doaj.art-841b79bf968e4ebaada3def77cf712d2 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T05:32:55Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-841b79bf968e4ebaada3def77cf712d22023-11-17T16:59:15ZengMDPI AGJournal of Clinical Medicine2077-03832023-03-01127259310.3390/jcm12072593Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF CyclesNikit Kadam0George Woodhead1Louise Kellam2Alison Campbell3Kanna Jayaprakasan4Derby Fertility Unit, University Hospitals of Deby and Burton, Derby DE22 3NE, UKCare Fertility, Nottingham NG8 6PZ, UKCare Fertility, Nottingham NG8 6PZ, UKCare Fertility, Nottingham NG8 6PZ, UKDerby Fertility Unit, University Hospitals of Deby and Burton, Derby DE22 3NE, UKThe rate of monozygotic twinning (MZT) has seen a gradual increase in recent years. Numerous parameters involved in ART procedures are blamed for this surge, even though the exact explanation is as yet unknown. Our study’s objectives were to determine the risk variables for monozygotic twinning after ART and to estimate their prevalence. We examined 25,794 IVF cycles for the incidence of monozygotic twinning in this observational analysis. Our study, which was carried out across seven tertiary IVF centres over the course of four years, found an overall MZT rate of 0.37% per embryo transfer procedure and 0.88% of all pregnancies. Monozygotic twinning was more commonly seen in fresh single-embryo transfer (SET) and blastocyst transfer cycles. Larger multicentre studies are needed to explore the potential risk variables.https://www.mdpi.com/2077-0383/12/7/2593monozygotic twinningassisted reproductionblastocyst transferIVFmultiple pregnancy |
| spellingShingle | Nikit Kadam George Woodhead Louise Kellam Alison Campbell Kanna Jayaprakasan Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles Journal of Clinical Medicine monozygotic twinning assisted reproduction blastocyst transfer IVF multiple pregnancy |
| title | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
| title_full | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
| title_fullStr | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
| title_full_unstemmed | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
| title_short | Odds and Predictors of Monozygotic Twinning in a Multicentre Cohort of 25,794 IVF Cycles |
| title_sort | odds and predictors of monozygotic twinning in a multicentre cohort of 25 794 ivf cycles |
| topic | monozygotic twinning assisted reproduction blastocyst transfer IVF multiple pregnancy |
| url | https://www.mdpi.com/2077-0383/12/7/2593 |
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