Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine epidemic diarrhea virus

Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine epidemic diarrhea virus

Abstract Background Porcine epidemic diarrhea caused by porcine epidemic diarrhea virus (PEDV) has led to serious economic losses to the swine industry worldwide. In this study, an oral recombinant Lactobacillus casei vaccine against PEDV infection targeting the intestinal microfold (M) cells and de...

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Bibliographic Details
Main Authors: Sunting Ma, Li Wang, Xuewei Huang, Xiaona Wang, Su Chen, Wen Shi, Xinyuan Qiao, Yanping Jiang, Lijie Tang, Yigang Xu, Yijing Li
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Microbial Cell Factories
Subjects:
Lactobacillus
Porcine epidemic diarrhea virus
Dendritic cell-targeting peptide
Microfold cell-targeting peptide
Oral immunization
Online Access:http://link.springer.com/article/10.1186/s12934-018-0861-7

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