A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders
Platelet-rich plasma (PRP) offers anti-inflammatory and regenerative properties through angiogenesis, cell differentiation, and proliferation. Although studied in many dermatologic conditions, its efficacy is not well-understood. Our objective is to review the use and effectiveness of PRP for dermat...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2023-12-01
|
| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2022.2142035 |
| _version_ | 1827816488941125632 |
|---|---|
| author | Jessica N. Pixley Madison K. Cook Rohan Singh Jorge Larrondo Amy J. McMichael |
| author_facet | Jessica N. Pixley Madison K. Cook Rohan Singh Jorge Larrondo Amy J. McMichael |
| author_sort | Jessica N. Pixley |
| collection | DOAJ |
| description | Platelet-rich plasma (PRP) offers anti-inflammatory and regenerative properties through angiogenesis, cell differentiation, and proliferation. Although studied in many dermatologic conditions, its efficacy is not well-understood. Our objective is to review the use and effectiveness of PRP for dermatologic conditions. A literature search was performed through PubMed and yielded 54 articles published between January 2000 and November 2021; articles written in English were reviewed. Intradermal injections were associated with increased hair density in androgenic alopecia. Successful treatment of inflammatory nail diseases with PRP has been reported. Improvement in psoriasis was described, but only two studies were available. PRP was associated with higher patient self-assessment scores of photoaging and fine lines. Treatment with PRP in melasma has been associated with improved subjective satisfaction, but not with objective measures of disease improvement. PRP can serve as a safe and potentially effective adjunct for hair loss, vitiligo, nonhealing wounds, photoaging, and acne scars. An important barrier to interpreting PRP research is lack of standardization of PRP preparation protocols, inconsistent clinical endpoints, and frequent combination treatments. However, PRP is relatively noninvasive, has a well-established safety profile, and patient satisfaction is often high as patients perceive great benefit from treatment with PRP. |
| first_indexed | 2024-03-12T00:15:01Z |
| format | Article |
| id | doaj.art-84202d0ae3e44a3bb1d70f6dafd64cb7 |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:15:01Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-84202d0ae3e44a3bb1d70f6dafd64cb72023-09-15T14:28:52ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532023-12-0134110.1080/09546634.2022.21420352142035A comprehensive review of platelet-rich plasma for the treatment of dermatologic disordersJessica N. Pixley0Madison K. Cook1Rohan Singh2Jorge Larrondo3Amy J. McMichael4Wake Forest Department of Dermatology, Medical Center BoulevardWake Forest Department of Dermatology, Medical Center BoulevardWake Forest Department of Dermatology, Medical Center BoulevardWake Forest Department of Dermatology, Medical Center BoulevardWake Forest Department of Dermatology, Medical Center BoulevardPlatelet-rich plasma (PRP) offers anti-inflammatory and regenerative properties through angiogenesis, cell differentiation, and proliferation. Although studied in many dermatologic conditions, its efficacy is not well-understood. Our objective is to review the use and effectiveness of PRP for dermatologic conditions. A literature search was performed through PubMed and yielded 54 articles published between January 2000 and November 2021; articles written in English were reviewed. Intradermal injections were associated with increased hair density in androgenic alopecia. Successful treatment of inflammatory nail diseases with PRP has been reported. Improvement in psoriasis was described, but only two studies were available. PRP was associated with higher patient self-assessment scores of photoaging and fine lines. Treatment with PRP in melasma has been associated with improved subjective satisfaction, but not with objective measures of disease improvement. PRP can serve as a safe and potentially effective adjunct for hair loss, vitiligo, nonhealing wounds, photoaging, and acne scars. An important barrier to interpreting PRP research is lack of standardization of PRP preparation protocols, inconsistent clinical endpoints, and frequent combination treatments. However, PRP is relatively noninvasive, has a well-established safety profile, and patient satisfaction is often high as patients perceive great benefit from treatment with PRP.http://dx.doi.org/10.1080/09546634.2022.2142035platelet-rich plasmadermatologyhair loss |
| spellingShingle | Jessica N. Pixley Madison K. Cook Rohan Singh Jorge Larrondo Amy J. McMichael A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders Journal of Dermatological Treatment platelet-rich plasma dermatology hair loss |
| title | A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders |
| title_full | A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders |
| title_fullStr | A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders |
| title_full_unstemmed | A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders |
| title_short | A comprehensive review of platelet-rich plasma for the treatment of dermatologic disorders |
| title_sort | comprehensive review of platelet rich plasma for the treatment of dermatologic disorders |
| topic | platelet-rich plasma dermatology hair loss |
| url | http://dx.doi.org/10.1080/09546634.2022.2142035 |
| work_keys_str_mv | AT jessicanpixley acomprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT madisonkcook acomprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT rohansingh acomprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT jorgelarrondo acomprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT amyjmcmichael acomprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT jessicanpixley comprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT madisonkcook comprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT rohansingh comprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT jorgelarrondo comprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders AT amyjmcmichael comprehensivereviewofplateletrichplasmaforthetreatmentofdermatologicdisorders |