Multivalent binding kinetics resolved by fluorescence proximity sensing
Fluorescence proximity sensing enables high throughput determination of binding affinities and kinetics of peptide inhibitors with varying valency and multivalent architecture.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03997-3 |
| _version_ | 1817979603653754880 |
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| author | Clemens Schulte Alice Soldà Sebastian Spänig Nathan Adams Ivana Bekić Werner Streicher Dominik Heider Ralf Strasser Hans Michael Maric |
| author_facet | Clemens Schulte Alice Soldà Sebastian Spänig Nathan Adams Ivana Bekić Werner Streicher Dominik Heider Ralf Strasser Hans Michael Maric |
| author_sort | Clemens Schulte |
| collection | DOAJ |
| description | Fluorescence proximity sensing enables high throughput determination of binding affinities and kinetics of peptide inhibitors with varying valency and multivalent architecture. |
| first_indexed | 2024-04-13T22:44:43Z |
| format | Article |
| id | doaj.art-8429778c1c484c93995699e093705efa |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T22:44:43Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-8429778c1c484c93995699e093705efa2022-12-22T02:26:27ZengNature PortfolioCommunications Biology2399-36422022-10-015111010.1038/s42003-022-03997-3Multivalent binding kinetics resolved by fluorescence proximity sensingClemens Schulte0Alice Soldà1Sebastian Spänig2Nathan Adams3Ivana Bekić4Werner Streicher5Dominik Heider6Ralf Strasser7Hans Michael Maric8Rudolf Virchow Center, Center for Integrative and Translational Bioimaging, University of WuerzburgDynamic Biosensors GmbH GermanyDepartment of Bioinformatics, Faculty of Mathematics and Computer Science, Philipps-University of MarburgNanotemper Technologies GmbHNanotemper Technologies GmbHNanotemper Technologies GmbHDepartment of Bioinformatics, Faculty of Mathematics and Computer Science, Philipps-University of MarburgDynamic Biosensors GmbH GermanyRudolf Virchow Center, Center for Integrative and Translational Bioimaging, University of WuerzburgFluorescence proximity sensing enables high throughput determination of binding affinities and kinetics of peptide inhibitors with varying valency and multivalent architecture.https://doi.org/10.1038/s42003-022-03997-3 |
| spellingShingle | Clemens Schulte Alice Soldà Sebastian Spänig Nathan Adams Ivana Bekić Werner Streicher Dominik Heider Ralf Strasser Hans Michael Maric Multivalent binding kinetics resolved by fluorescence proximity sensing Communications Biology |
| title | Multivalent binding kinetics resolved by fluorescence proximity sensing |
| title_full | Multivalent binding kinetics resolved by fluorescence proximity sensing |
| title_fullStr | Multivalent binding kinetics resolved by fluorescence proximity sensing |
| title_full_unstemmed | Multivalent binding kinetics resolved by fluorescence proximity sensing |
| title_short | Multivalent binding kinetics resolved by fluorescence proximity sensing |
| title_sort | multivalent binding kinetics resolved by fluorescence proximity sensing |
| url | https://doi.org/10.1038/s42003-022-03997-3 |
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