Multivalent binding kinetics resolved by fluorescence proximity sensing

Fluorescence proximity sensing enables high throughput determination of binding affinities and kinetics of peptide inhibitors with varying valency and multivalent architecture.

Bibliographic Details
Main Authors: Clemens Schulte, Alice Soldà, Sebastian Spänig, Nathan Adams, Ivana Bekić, Werner Streicher, Dominik Heider, Ralf Strasser, Hans Michael Maric
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03997-3

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