18 Years Surgical Experience With Mediastinal Mature Teratoma
Few studies have examined the surgical outcomes of mediastinal mature teratoma in Taiwan. In the present study, the clinicopathological characteristics of mature teratoma and their impact on surgical outcome were analyzed. Methods: From 1988 to 2005, 57 cases of mediastinal mature teratoma were revi...
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| Format: | Article |
| Language: | English |
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Elsevier
2010-04-01
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| Series: | Journal of the Formosan Medical Association |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S092966461060054X |
| _version_ | 1818336103126532096 |
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| author | Chin-Chih Chang Yih-Leong Chang Jang-Ming Lee Jin-Shing Chen Hsao-Hsun Hsu Pei-Ming Huang Yung-Chie Lee |
| author_facet | Chin-Chih Chang Yih-Leong Chang Jang-Ming Lee Jin-Shing Chen Hsao-Hsun Hsu Pei-Ming Huang Yung-Chie Lee |
| author_sort | Chin-Chih Chang |
| collection | DOAJ |
| description | Few studies have examined the surgical outcomes of mediastinal mature teratoma in Taiwan. In the present study, the clinicopathological characteristics of mature teratoma and their impact on surgical outcome were analyzed.
Methods: From 1988 to 2005, 57 cases of mediastinal mature teratoma were reviewed. We collected and analyzed data about patient age, sex, symptoms, blood sugar, pulmonary function, diagnosis, tumor size, histopathological features, operative methods, operative time, tumor adhesion, blood loss, ventilator requirement, intensive care unit stay, chest tube requirement, and postoperative hospital stay.
Results: There were 18 male and 39 female patients with a median age of 27 years. Forty-three patients received conventional open surgery, whereas 14 received video-assisted thoracoscopic surgery. The patients in the thoracoscopic group had a decreased operative time (106.4 ± 35.7 min vs. 205.4 ± 75.7 min, p = 0.038), fewer ventilator days (0.2 ± 0.4 vs. 0.5 ± 0.8, p = 0.034), and a shorter stay in the intensive care unit (0.6 ± 0.8 days vs. 1.5 ± 1.4 days, p = 0.030). Pancreatic tissue was identified in 21 of 57 tumors (36.8%). The patients with tumors that contained pancreatic tissue had more presenting symptoms and complicated surgery than those whose tumors were without pancreatic tissue (76.2% vs. 33.3%, p = 0.002, and 42.9% vs. 11.1%, p = 0.008). The patients with symptoms had a higher incidence of complicated surgery than those without (39.3% vs. 6.9%, p = 0.004).
Conclusion: Mediastinal mature teratoma commonly occurs in young women. Thoracoscopic surgery is a feasible technique for mediastinal mature teratoma resection if no dense adhesions are found during preoperative assessment. The presence of symptoms might be a relative contraindication for thoracoscopic teratoma resection because of its association with surgical complications. |
| first_indexed | 2024-12-13T14:34:00Z |
| format | Article |
| id | doaj.art-84299ab80bd8441ebe0204ee835eb8da |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-13T14:34:00Z |
| publishDate | 2010-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-84299ab80bd8441ebe0204ee835eb8da2022-12-21T23:41:46ZengElsevierJournal of the Formosan Medical Association0929-66462010-04-01109428729210.1016/S0929-6646(10)60054-X18 Years Surgical Experience With Mediastinal Mature TeratomaChin-Chih Chang0Yih-Leong Chang1Jang-Ming Lee2Jin-Shing Chen3Hsao-Hsun Hsu4Pei-Ming Huang5Yung-Chie Lee6Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDepartment of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDivision of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDivision of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDivision of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDivision of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDivision of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanFew studies have examined the surgical outcomes of mediastinal mature teratoma in Taiwan. In the present study, the clinicopathological characteristics of mature teratoma and their impact on surgical outcome were analyzed. Methods: From 1988 to 2005, 57 cases of mediastinal mature teratoma were reviewed. We collected and analyzed data about patient age, sex, symptoms, blood sugar, pulmonary function, diagnosis, tumor size, histopathological features, operative methods, operative time, tumor adhesion, blood loss, ventilator requirement, intensive care unit stay, chest tube requirement, and postoperative hospital stay. Results: There were 18 male and 39 female patients with a median age of 27 years. Forty-three patients received conventional open surgery, whereas 14 received video-assisted thoracoscopic surgery. The patients in the thoracoscopic group had a decreased operative time (106.4 ± 35.7 min vs. 205.4 ± 75.7 min, p = 0.038), fewer ventilator days (0.2 ± 0.4 vs. 0.5 ± 0.8, p = 0.034), and a shorter stay in the intensive care unit (0.6 ± 0.8 days vs. 1.5 ± 1.4 days, p = 0.030). Pancreatic tissue was identified in 21 of 57 tumors (36.8%). The patients with tumors that contained pancreatic tissue had more presenting symptoms and complicated surgery than those whose tumors were without pancreatic tissue (76.2% vs. 33.3%, p = 0.002, and 42.9% vs. 11.1%, p = 0.008). The patients with symptoms had a higher incidence of complicated surgery than those without (39.3% vs. 6.9%, p = 0.004). Conclusion: Mediastinal mature teratoma commonly occurs in young women. Thoracoscopic surgery is a feasible technique for mediastinal mature teratoma resection if no dense adhesions are found during preoperative assessment. The presence of symptoms might be a relative contraindication for thoracoscopic teratoma resection because of its association with surgical complications.http://www.sciencedirect.com/science/article/pii/S092966461060054Xmediastinal neoplasmsminimally invasive surgical proceduresthoracoscopy |
| spellingShingle | Chin-Chih Chang Yih-Leong Chang Jang-Ming Lee Jin-Shing Chen Hsao-Hsun Hsu Pei-Ming Huang Yung-Chie Lee 18 Years Surgical Experience With Mediastinal Mature Teratoma Journal of the Formosan Medical Association mediastinal neoplasms minimally invasive surgical procedures thoracoscopy |
| title | 18 Years Surgical Experience With Mediastinal Mature Teratoma |
| title_full | 18 Years Surgical Experience With Mediastinal Mature Teratoma |
| title_fullStr | 18 Years Surgical Experience With Mediastinal Mature Teratoma |
| title_full_unstemmed | 18 Years Surgical Experience With Mediastinal Mature Teratoma |
| title_short | 18 Years Surgical Experience With Mediastinal Mature Teratoma |
| title_sort | 18 years surgical experience with mediastinal mature teratoma |
| topic | mediastinal neoplasms minimally invasive surgical procedures thoracoscopy |
| url | http://www.sciencedirect.com/science/article/pii/S092966461060054X |
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