Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease Patients
INTRODUCTION: Coronovirus 2019 ( Covid-19) infection has been related to increased mortality amongst patients with lung disease. In this study it was aimed to showed the mortality rate and possible prognostic factors related to Covid-19 in connective tissue disease related interstitial lung disease...
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| Format: | Article |
| Language: | English |
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Van Yuzuncu Yil University, School of Medicine
2022-07-01
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| Series: | Van Tıp Dergisi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-67790 |
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| author | Hasan Satış Yasemin Ünsal Abdurrahman Tufan |
| author_facet | Hasan Satış Yasemin Ünsal Abdurrahman Tufan |
| author_sort | Hasan Satış |
| collection | DOAJ |
| description | INTRODUCTION: Coronovirus 2019 ( Covid-19) infection has been related to increased mortality amongst patients with lung disease. In this study it was aimed to showed the mortality rate and possible prognostic factors related to Covid-19 in connective tissue disease related interstitial lung disease patients (CTD-ILD)
METHODS: In a tertiary referral center,patients with previously diagnosed CTD-ILD retrospectively reviewed. Between 1th April 2020 to 1 th April 2021 patients data related to ILD disease, Covid-19 infection and mortality obtained from electronic records retrospectively. The primary outcome was death at day 30 of COVID-19 infection
RESULTS: There were 271patients diagnosed with CTD-ILD. 74 patients had Covid-19 infection, which was confirmed by polymerase chain reaction. 29 patients were dead during the followed-up period of whom 13 patients had Covid-19 infection-related mortality (17.5% vs 8.1%, p: 0.045). Covid-19 infection related to mortality was more frequently seen in patients with decreased forced vital capacity, smoking history, extended disease and rheumatoid arthritis. On multivariate regression analysis, only decreased forced vital capacity were related to poor outcomes.
DISCUSSION AND CONCLUSION: Covid-19 infection is related to increased risk of mortality in CTD-ILD patients. Decreased forced vital capacity is a poor prognostic risk factor |
| first_indexed | 2024-03-09T09:26:08Z |
| format | Article |
| id | doaj.art-842cf868bee649989c4816370dc66d27 |
| institution | Directory Open Access Journal |
| issn | 2587-0351 |
| language | English |
| last_indexed | 2024-03-09T09:26:08Z |
| publishDate | 2022-07-01 |
| publisher | Van Yuzuncu Yil University, School of Medicine |
| record_format | Article |
| series | Van Tıp Dergisi |
| spelling | doaj.art-842cf868bee649989c4816370dc66d272023-12-02T05:58:36ZengVan Yuzuncu Yil University, School of MedicineVan Tıp Dergisi2587-03512022-07-0129333233610.5505/vtd.2022.67790VTD-67790Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease PatientsHasan Satış0Yasemin Ünsal1Abdurrahman Tufan2Gazi University Faculty of Medicine Hospital Rheumatology Department,AnkaraGazi University Faculty of Medicine Hospital Internal Medicine Department,AnkaraGazi University Faculty of Medicine Hospital Rheumatology Department,AnkaraINTRODUCTION: Coronovirus 2019 ( Covid-19) infection has been related to increased mortality amongst patients with lung disease. In this study it was aimed to showed the mortality rate and possible prognostic factors related to Covid-19 in connective tissue disease related interstitial lung disease patients (CTD-ILD) METHODS: In a tertiary referral center,patients with previously diagnosed CTD-ILD retrospectively reviewed. Between 1th April 2020 to 1 th April 2021 patients data related to ILD disease, Covid-19 infection and mortality obtained from electronic records retrospectively. The primary outcome was death at day 30 of COVID-19 infection RESULTS: There were 271patients diagnosed with CTD-ILD. 74 patients had Covid-19 infection, which was confirmed by polymerase chain reaction. 29 patients were dead during the followed-up period of whom 13 patients had Covid-19 infection-related mortality (17.5% vs 8.1%, p: 0.045). Covid-19 infection related to mortality was more frequently seen in patients with decreased forced vital capacity, smoking history, extended disease and rheumatoid arthritis. On multivariate regression analysis, only decreased forced vital capacity were related to poor outcomes. DISCUSSION AND CONCLUSION: Covid-19 infection is related to increased risk of mortality in CTD-ILD patients. Decreased forced vital capacity is a poor prognostic risk factorhttps://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-67790connective tissue diseaseinterstitial lung diseasecovid-19 infectionmortality |
| spellingShingle | Hasan Satış Yasemin Ünsal Abdurrahman Tufan Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease Patients Van Tıp Dergisi connective tissue disease interstitial lung disease covid-19 infection mortality |
| title | Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease Patients |
| title_full | Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease Patients |
| title_fullStr | Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease Patients |
| title_full_unstemmed | Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease Patients |
| title_short | Covid-19 Course in Connective Tissue Disease-Related Interstitial Lung Disease Patients |
| title_sort | covid 19 course in connective tissue disease related interstitial lung disease patients |
| topic | connective tissue disease interstitial lung disease covid-19 infection mortality |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-67790 |
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