Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells

Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells

ExoY is among the effectors that are injected by the type III secretion system (T3SS) of Pseudomonas aeruginosa into host cells. Inside eukaryotic cells, ExoY interacts with F-actin, which stimulates its potent nucleotidyl cyclase activity to produce cyclic nucleotide monophosphates (cNMPs). ExoY ha...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hazel Silistre, Dorothée Raoux-Barbot, Federica Mancinelli, Flora Sangouard, Alice Dupin, Alexander Belyy, Vincent Deruelle, Louis Renault, Daniel Ladant, Lhousseine Touqui, Undine Mechold
التنسيق: مقال
اللغة:English
منشور في: Frontiers Media S.A. 2021-10-01
سلاسل:Frontiers in Microbiology
الموضوعات:
ExoY
nucleotidyl cyclase
Pseudomonas aeruginosa
cystic fibrosis
cGMP
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fmicb.2021.666097/full

الانترنت

https://www.frontiersin.org/articles/10.3389/fmicb.2021.666097/full

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