Network Toxicology and Molecular Docking to Investigate the Non-AChE Mechanisms of Organophosphate-Induced Neurodevelopmental Toxicity

Network Toxicology and Molecular Docking to Investigate the Non-AChE Mechanisms of Organophosphate-Induced Neurodevelopmental Toxicity

Organophosphate pesticides (OPs) are toxic substances that contaminate aquatic environments, interfere with the development of the nervous system, and induce Neurodevelopmental Toxicity (NDT) in animals and humans. The canonical mechanism of OP neurotoxicity involves the inhibition of acetylcholines...

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Bibliographic Details
Main Authors: Juliana Alves da Costa Ribeiro Souza, Terezinha Souza, Isadora Louise Alves da Costa Ribeiro Quintans, Davi Farias
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Toxics
Subjects:
aquatic contamination
ecotoxicology
environmental contamination
enrichment analysis
network biology
neurodevelopmental disorders
Online Access:https://www.mdpi.com/2305-6304/11/8/710

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https://www.mdpi.com/2305-6304/11/8/710

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