Sex and gender influence on immunity and autoimmunity
Autoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors.
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1142723/full |
| _version_ | 1797819824108208128 |
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| author | Robert G. Lahita Robert G. Lahita |
| author_facet | Robert G. Lahita Robert G. Lahita |
| author_sort | Robert G. Lahita |
| collection | DOAJ |
| description | Autoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors. |
| first_indexed | 2024-03-13T09:28:19Z |
| format | Article |
| id | doaj.art-843daf881fae4d2e93ec9c7f7472ccf1 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-03-13T09:28:19Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-843daf881fae4d2e93ec9c7f7472ccf12023-05-26T04:34:56ZengFrontiers Media S.A.Frontiers in Immunology1664-32242023-05-011410.3389/fimmu.2023.11427231142723Sex and gender influence on immunity and autoimmunityRobert G. Lahita0Robert G. Lahita1Hackensack Meridian School of Medicine, Hackensack, NJ, United StatesInstitute for Autoimmune and Rheumatic Disease, St. Joseph Health, Wayne, NJ, United StatesAutoimmune diseases are skewed toward one biological sex or another. This is the obvious observation of many decades, and it remains unexplained. Females predominate with most autoimmune diseases. The reasons for this predilection are an interplay of genetic, epigenetic and hormonal factors.https://www.frontiersin.org/articles/10.3389/fimmu.2023.1142723/fullprolactinDHEASLE - systemic lupus erthematosustestosterone (androgen)estrogengenetic |
| spellingShingle | Robert G. Lahita Robert G. Lahita Sex and gender influence on immunity and autoimmunity Frontiers in Immunology prolactin DHEA SLE - systemic lupus erthematosus testosterone (androgen) estrogen genetic |
| title | Sex and gender influence on immunity and autoimmunity |
| title_full | Sex and gender influence on immunity and autoimmunity |
| title_fullStr | Sex and gender influence on immunity and autoimmunity |
| title_full_unstemmed | Sex and gender influence on immunity and autoimmunity |
| title_short | Sex and gender influence on immunity and autoimmunity |
| title_sort | sex and gender influence on immunity and autoimmunity |
| topic | prolactin DHEA SLE - systemic lupus erthematosus testosterone (androgen) estrogen genetic |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1142723/full |
| work_keys_str_mv | AT robertglahita sexandgenderinfluenceonimmunityandautoimmunity AT robertglahita sexandgenderinfluenceonimmunityandautoimmunity |