Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literature
Endometrial endometrioid type cancer is a common gynaecological cancer for which the standard surgical management includes hysterectomy and bilateral salpingo-oophorectomy. The value of oophorectomy is to remove occult ovarian disease. It is estimated that 5 % of low grade endometrioid adenocarcinom...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | Gynecologic Oncology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352578922001412 |
| _version_ | 1798020609688469504 |
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| author | Sophia Hill Lyndal Anderson Selvan Pather |
| author_facet | Sophia Hill Lyndal Anderson Selvan Pather |
| author_sort | Sophia Hill |
| collection | DOAJ |
| description | Endometrial endometrioid type cancer is a common gynaecological cancer for which the standard surgical management includes hysterectomy and bilateral salpingo-oophorectomy. The value of oophorectomy is to remove occult ovarian disease. It is estimated that 5 % of low grade endometrioid adenocarcinoma will have concurrent ovarian involvement (3 % synchronous tumours, 2 % ovarian metastases), of which only 1 % will be microscopic. Ovarian preservation at the time of surgery can be considered, especially in early-stage disease or premenopausal women. We describe a case of metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium (FIGO stage 1a), in a postmenopausal woman who declined primary oophorectomy. This case was without genetic predisposition and recurred 12 months after initial surgical treatment. This case is incongruent with what has previously been understood for FIGO stage 1a endometrial endometrioid adenocarcinoma and highlights that even disease seemingly confined to the endometrium can metastasise microscopically to the ovaries. |
| first_indexed | 2024-04-11T17:00:15Z |
| format | Article |
| id | doaj.art-843de52ce7134af3939c21a70384ca5b |
| institution | Directory Open Access Journal |
| issn | 2352-5789 |
| language | English |
| last_indexed | 2024-04-11T17:00:15Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gynecologic Oncology Reports |
| spelling | doaj.art-843de52ce7134af3939c21a70384ca5b2022-12-22T04:13:10ZengElsevierGynecologic Oncology Reports2352-57892022-10-0143101061Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literatureSophia Hill0Lyndal Anderson1Selvan Pather2Gynaecologic Oncology, Chris O’Brien Lifehouse, Camperdown 2050, Australia; Corresponding author at: Obstetrics and Gynaecology Trainee, Chris O’Brien Lifehouse, 119-143 Missenden Road, Camperdown NSW 2050, PO BOX M33 Missenden Road, NSW 2050, Australia.Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown 2050, Australia; Sydney Medical School, University of Sydney, Camperdown 2006, Australia; Western Sydney University, Penrith 2751, AustraliaGynaecologic Oncology, Chris O’Brien Lifehouse, Camperdown 2050, Australia; Sydney Medical School, University of Sydney, Camperdown 2006, AustraliaEndometrial endometrioid type cancer is a common gynaecological cancer for which the standard surgical management includes hysterectomy and bilateral salpingo-oophorectomy. The value of oophorectomy is to remove occult ovarian disease. It is estimated that 5 % of low grade endometrioid adenocarcinoma will have concurrent ovarian involvement (3 % synchronous tumours, 2 % ovarian metastases), of which only 1 % will be microscopic. Ovarian preservation at the time of surgery can be considered, especially in early-stage disease or premenopausal women. We describe a case of metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium (FIGO stage 1a), in a postmenopausal woman who declined primary oophorectomy. This case was without genetic predisposition and recurred 12 months after initial surgical treatment. This case is incongruent with what has previously been understood for FIGO stage 1a endometrial endometrioid adenocarcinoma and highlights that even disease seemingly confined to the endometrium can metastasise microscopically to the ovaries.http://www.sciencedirect.com/science/article/pii/S2352578922001412Endometrial CancerGrade 1 Endometrioid AdenocarcinomaFIGO Stage 1aMetastatic Ovarian Cancer |
| spellingShingle | Sophia Hill Lyndal Anderson Selvan Pather Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literature Gynecologic Oncology Reports Endometrial Cancer Grade 1 Endometrioid Adenocarcinoma FIGO Stage 1a Metastatic Ovarian Cancer |
| title | Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literature |
| title_full | Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literature |
| title_fullStr | Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literature |
| title_full_unstemmed | Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literature |
| title_short | Metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium; a case report and review of the literature |
| title_sort | metastatic ovarian disease following surgical management of grade 1 endometrial endometrioid adenocarcinoma confined to the endometrium a case report and review of the literature |
| topic | Endometrial Cancer Grade 1 Endometrioid Adenocarcinoma FIGO Stage 1a Metastatic Ovarian Cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2352578922001412 |
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