Uncertain futures and unsolicited findings in pediatric genomic sequencing: guidelines for return of results in cases of developmental delay

Uncertain futures and unsolicited findings in pediatric genomic sequencing: guidelines for return of results in cases of developmental delay

Abstract Background Massively parallel sequencing techniques, such as whole exome sequencing (WES) and whole genome sequencing (WGS), may reveal unsolicited findings (UFs) unrelated to the diagnostic aim. Such techniques are frequently used for diagnostic purposes in pediatric cases of developmental...

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Bibliographic Details
Main Authors: Candice Cornelis, Wybo Dondorp, Ineke Bolt, Guido de Wert, Marieke van Summeren, Eva Brilstra, Nine Knoers, Annelien L. Bredenoord
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Medical Ethics
Subjects:
Unsolicited findings
Genomic sequencing
Children
Return of results
Future autonomy
Online Access:https://doi.org/10.1186/s12910-023-00977-y

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