Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation Model
Lijuan Liu,1,2,* Wenzhuo Huang,1,2,* Zhuoer Huang,1,3 Jiaxin Liu,1,3 Xiaoyuan Zheng,1 Jing Tang,1,2 Ying Wu,1 Xiaohui Wang,1 Yongzhen Liao,4 Li Cong1 1School of Medicine, Hunan Normal University, Changsha, People’s Republic of China; 2Teaching and Research Section of Clinical Nursing...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-12-01
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| Series: | Patient Preference and Adherence |
| Subjects: | |
| Online Access: | https://www.dovepress.com/relationship-between-family-caregiver-burden-and-medication-adherence--peer-reviewed-fulltext-article-PPA |
| _version_ | 1797979746225618944 |
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| author | Liu L Huang W Huang Z Liu J Zheng X Tang J Wu Y Wang X Liao Y Cong L |
| author_facet | Liu L Huang W Huang Z Liu J Zheng X Tang J Wu Y Wang X Liao Y Cong L |
| author_sort | Liu L |
| collection | DOAJ |
| description | Lijuan Liu,1,2,* Wenzhuo Huang,1,2,* Zhuoer Huang,1,3 Jiaxin Liu,1,3 Xiaoyuan Zheng,1 Jing Tang,1,2 Ying Wu,1 Xiaohui Wang,1 Yongzhen Liao,4 Li Cong1 1School of Medicine, Hunan Normal University, Changsha, People’s Republic of China; 2Teaching and Research Section of Clinical Nursing, Xiangya Hospital of Central South University, Changsha, People’s Republic of China; 3Xiangya School of Nursing, Central South University, Changsha, People’s Republic of China; 4Shunde Polytechnic, Foshan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li Cong, School of Medicine, Hunan Normal University, Changsha, People’s Republic of China, Tel/Fax +86-0731-88912446, Email congli@hunnu.edu.cnBackground: Oral anticoagulant is a necessary long-term treatment after mechanical valve replacement (MVR), and medication adherence has a great impact on patients with MVR. Although family caregiver burden is negatively correlated with medication adherence, little is known about the underlying mechanism.Purpose: To test whether family caregiver burden influences medication adherence through post-traumatic growth or medication literacy in patients with MVR.Patients and Methods: A total of 206 patients after MVR were included in this cross-sectional study from July 2021 to December 2021. Data regarding medication adherence, family caregiver burden, post-traumatic growth, and medication literacy were collected by questionnaires. Data were analyzed through SPSS, and pathway analysis was conducted by using AMOS, based on the bootstrapping method.Results: Post-traumatic growth was positively associated with medication adherence (r = 0.284, P < 0.05). Post-traumatic growth independently mediated the association of family caregiver burden on medication adherence [β = 0.32, 95% confidence intervals: (− 0.016, − 0.008)]. The mediated effect value for post-traumatic growth was 0.07, accounting for 24.14% of the total effect. The model’s fit indices were adequate.Conclusion: The mediating effect of post-traumatic growth between family caregiver burden and medication adherence existed in patients with MVR. Interventions considering post-traumatic growth may be useful to increase medication adherence and improve patient rehabilitation.Keywords: medication adherence, family caregiver burden, post-traumatic growth, medication literacy, mediation analyses, mechanical valve replacement |
| first_indexed | 2024-04-11T05:43:34Z |
| format | Article |
| id | doaj.art-84401ec3b61f4a8c91dc08222a3d6562 |
| institution | Directory Open Access Journal |
| issn | 1177-889X |
| language | English |
| last_indexed | 2024-04-11T05:43:34Z |
| publishDate | 2022-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Patient Preference and Adherence |
| spelling | doaj.art-84401ec3b61f4a8c91dc08222a3d65622022-12-22T04:42:19ZengDove Medical PressPatient Preference and Adherence1177-889X2022-12-01Volume 163371338280485Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation ModelLiu LHuang WHuang ZLiu JZheng XTang JWu YWang XLiao YCong LLijuan Liu,1,2,* Wenzhuo Huang,1,2,* Zhuoer Huang,1,3 Jiaxin Liu,1,3 Xiaoyuan Zheng,1 Jing Tang,1,2 Ying Wu,1 Xiaohui Wang,1 Yongzhen Liao,4 Li Cong1 1School of Medicine, Hunan Normal University, Changsha, People’s Republic of China; 2Teaching and Research Section of Clinical Nursing, Xiangya Hospital of Central South University, Changsha, People’s Republic of China; 3Xiangya School of Nursing, Central South University, Changsha, People’s Republic of China; 4Shunde Polytechnic, Foshan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li Cong, School of Medicine, Hunan Normal University, Changsha, People’s Republic of China, Tel/Fax +86-0731-88912446, Email congli@hunnu.edu.cnBackground: Oral anticoagulant is a necessary long-term treatment after mechanical valve replacement (MVR), and medication adherence has a great impact on patients with MVR. Although family caregiver burden is negatively correlated with medication adherence, little is known about the underlying mechanism.Purpose: To test whether family caregiver burden influences medication adherence through post-traumatic growth or medication literacy in patients with MVR.Patients and Methods: A total of 206 patients after MVR were included in this cross-sectional study from July 2021 to December 2021. Data regarding medication adherence, family caregiver burden, post-traumatic growth, and medication literacy were collected by questionnaires. Data were analyzed through SPSS, and pathway analysis was conducted by using AMOS, based on the bootstrapping method.Results: Post-traumatic growth was positively associated with medication adherence (r = 0.284, P < 0.05). Post-traumatic growth independently mediated the association of family caregiver burden on medication adherence [β = 0.32, 95% confidence intervals: (− 0.016, − 0.008)]. The mediated effect value for post-traumatic growth was 0.07, accounting for 24.14% of the total effect. The model’s fit indices were adequate.Conclusion: The mediating effect of post-traumatic growth between family caregiver burden and medication adherence existed in patients with MVR. Interventions considering post-traumatic growth may be useful to increase medication adherence and improve patient rehabilitation.Keywords: medication adherence, family caregiver burden, post-traumatic growth, medication literacy, mediation analyses, mechanical valve replacementhttps://www.dovepress.com/relationship-between-family-caregiver-burden-and-medication-adherence--peer-reviewed-fulltext-article-PPAmedication adherencefamily caregiver burdenpost-traumatic growthmedication literacymediation analysesmechanical valve replacement |
| spellingShingle | Liu L Huang W Huang Z Liu J Zheng X Tang J Wu Y Wang X Liao Y Cong L Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation Model Patient Preference and Adherence medication adherence family caregiver burden post-traumatic growth medication literacy mediation analyses mechanical valve replacement |
| title | Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation Model |
| title_full | Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation Model |
| title_fullStr | Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation Model |
| title_full_unstemmed | Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation Model |
| title_short | Relationship Between Family Caregiver Burden and Medication Adherence in Patients with Mechanical Valve Replacement: A Structural Equation Model |
| title_sort | relationship between family caregiver burden and medication adherence in patients with mechanical valve replacement a structural equation model |
| topic | medication adherence family caregiver burden post-traumatic growth medication literacy mediation analyses mechanical valve replacement |
| url | https://www.dovepress.com/relationship-between-family-caregiver-burden-and-medication-adherence--peer-reviewed-fulltext-article-PPA |
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