Short-Form Thymic Stromal Lymphopoietin (sfTSLP) Is the Predominant Isoform Expressed by Gynaecologic Cancers and Promotes Tumour Growth

Short-Form Thymic Stromal Lymphopoietin (sfTSLP) Is the Predominant Isoform Expressed by Gynaecologic Cancers and Promotes Tumour Growth

Thymic stromal lymphopoietin (TSLP) is an epithelial cell derived cytokine belonging to the IL-7 family and a key initiator of allergic inflammation. Two main isoforms of TSLP, classified as long- (lfTSLP) and short-form (sfTSLP), have been reported in human, but their expression patterns and role(s...

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Bibliographic Details
Main Authors: Loucia Kit Ying Chan, Tat San Lau, Kit Ying Chung, Chit Tam, Tak Hong Cheung, So Fan Yim, Jacqueline Ho Sze Lee, Ricky Wai Tak Leung, Jing Qin, Yvonne Yan Yan Or, Kwok Wai Lo, Joseph Kwong
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
TSLP
short isoform
ovarian cancer
endometrial cancer
epigenetic regulation
tumour promotion
Online Access:https://www.mdpi.com/2072-6694/13/5/980

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