Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes

Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes

Insulin-stimulated glucose transport is a characteristic property of adipocytes and muscle cells and involves the regulated delivery of glucose transporter (GLUT4)-containing vesicles from intracellular stores to the cell surface. Fusion of these vesicles results in increased numbers of GLUT4 molecu...

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Bibliographic Details
Main Authors: Silke Morris, Niall D. Geoghegan, Jessica B.A. Sadler, Anna M. Koester, Hannah L. Black, Marco Laub, Lucy Miller, Linda Heffernan, Jeremy C. Simpson, Cynthia C. Mastick, Jon Cooper, Nikolaj Gadegaard, Nia J. Bryant, Gwyn W. Gould
Format: Article
Language:English
Published: PeerJ Inc. 2020-03-01
Series:PeerJ
Subjects:
Membrane
Transport
Insulin
Diabetes
GLUT4
Endosome
Online Access:https://peerj.com/articles/8751.pdf

Internet

https://peerj.com/articles/8751.pdf

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