Estimation of COVID-19 spread curves integrating global data and borrowing information.

Currently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no drugs or other therapeutics approved by the US Food and Dru...

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Main Authors: Se Yoon Lee, Bowen Lei, Bani Mallick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236860
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author Se Yoon Lee
Bowen Lei
Bani Mallick
author_facet Se Yoon Lee
Bowen Lei
Bani Mallick
author_sort Se Yoon Lee
collection DOAJ
description Currently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no drugs or other therapeutics approved by the US Food and Drug Administration to prevent or treat COVID-19: information on the disease is very limited and scattered even if it exists. This motivates the use of data integration, combining data from diverse sources and eliciting useful information with a unified view of them. In this paper, we propose a Bayesian hierarchical model that integrates global data for real-time prediction of infection trajectory for multiple countries. Because the proposed model takes advantage of borrowing information across multiple countries, it outperforms an existing individual country-based model. As fully Bayesian way has been adopted, the model provides a powerful predictive tool endowed with uncertainty quantification. Additionally, a joint variable selection technique has been integrated into the proposed modeling scheme, which aimed to identify possible country-level risk factors for severe disease due to COVID-19.
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spelling doaj.art-844ec3acb481401c98f459df18e9d35e2022-12-21T22:35:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01157e023686010.1371/journal.pone.0236860Estimation of COVID-19 spread curves integrating global data and borrowing information.Se Yoon LeeBowen LeiBani MallickCurrently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no drugs or other therapeutics approved by the US Food and Drug Administration to prevent or treat COVID-19: information on the disease is very limited and scattered even if it exists. This motivates the use of data integration, combining data from diverse sources and eliciting useful information with a unified view of them. In this paper, we propose a Bayesian hierarchical model that integrates global data for real-time prediction of infection trajectory for multiple countries. Because the proposed model takes advantage of borrowing information across multiple countries, it outperforms an existing individual country-based model. As fully Bayesian way has been adopted, the model provides a powerful predictive tool endowed with uncertainty quantification. Additionally, a joint variable selection technique has been integrated into the proposed modeling scheme, which aimed to identify possible country-level risk factors for severe disease due to COVID-19.https://doi.org/10.1371/journal.pone.0236860
spellingShingle Se Yoon Lee
Bowen Lei
Bani Mallick
Estimation of COVID-19 spread curves integrating global data and borrowing information.
PLoS ONE
title Estimation of COVID-19 spread curves integrating global data and borrowing information.
title_full Estimation of COVID-19 spread curves integrating global data and borrowing information.
title_fullStr Estimation of COVID-19 spread curves integrating global data and borrowing information.
title_full_unstemmed Estimation of COVID-19 spread curves integrating global data and borrowing information.
title_short Estimation of COVID-19 spread curves integrating global data and borrowing information.
title_sort estimation of covid 19 spread curves integrating global data and borrowing information
url https://doi.org/10.1371/journal.pone.0236860
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AT bowenlei estimationofcovid19spreadcurvesintegratingglobaldataandborrowinginformation
AT banimallick estimationofcovid19spreadcurvesintegratingglobaldataandborrowinginformation