Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep

The purpose of this research was to investigate the acute effects of Tarantula cubensis extract (Theranekron, 1:100/D2, Richter Pharma, Austria) on some serum enzymes and trace elements, and the cardiovascular system in sheep. Seven sheep (age 6 months, 35±10 kg) were used in this study. Theranekron...

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Main Authors: Remzi GONUL, Lora KOENHEMSİ, Handan AYDIN, Tevfik GULYASAR, Hasret DEMIRCAN YARDIBI, Erman OR, Gulhan HOSTURK, Abdulkadir UYSAL, Bora BARUTCU
Format: Article
Language:English
Published: Istanbul University 2015-01-01
Series:İstanbul Üniversitesi Veteriner Fakültesi Dergisi
Subjects:
Online Access:http://www.journals.istanbul.edu.tr/iuvfd/article/view/5000079774/5000074145
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author Remzi GONUL
Lora KOENHEMSİ
Handan AYDIN
Tevfik GULYASAR
Hasret DEMIRCAN YARDIBI
Erman OR
Gulhan HOSTURK
Abdulkadir UYSAL
Bora BARUTCU
author_facet Remzi GONUL
Lora KOENHEMSİ
Handan AYDIN
Tevfik GULYASAR
Hasret DEMIRCAN YARDIBI
Erman OR
Gulhan HOSTURK
Abdulkadir UYSAL
Bora BARUTCU
author_sort Remzi GONUL
collection DOAJ
description The purpose of this research was to investigate the acute effects of Tarantula cubensis extract (Theranekron, 1:100/D2, Richter Pharma, Austria) on some serum enzymes and trace elements, and the cardiovascular system in sheep. Seven sheep (age 6 months, 35±10 kg) were used in this study. Theranekron was applied in 6 ml doses subcutaneously. It was determined that in the serum Urea, Creatinin, ALT, ALP, G-GT, LDH, Ca and P levels were increased and T. protein, Mg, Cu, Fe, Zn and Se levels were decreased. The important results obtained after the treatment with Theranekron on cardiovascular system were blood pressure increases and some morphological changes in ECG. We concluded the Theranekron treatment can cause adverse effects in sheep and further investigation of the efficacy of Theranekron treatment is warranted.
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spelling doaj.art-844eef92be854eb48bdfcbf9c213ee712023-02-15T16:21:34ZengIstanbul Universityİstanbul Üniversitesi Veteriner Fakültesi Dergisi0250-28360250-28362015-01-01411798310.16988/iuvfd.2015.25554Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in SheepRemzi GONUL0Lora KOENHEMSİ1 Handan AYDIN2Tevfik GULYASAR3Hasret DEMIRCAN YARDIBI4Erman OR5Gulhan HOSTURK6Abdulkadir UYSAL7Bora BARUTCU8Istanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Istanbul, TurkeyTrakya University, Medical School, Department of Biophysic, Edirne, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Biochemistry, Istanbul, Turkey Istanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Biochemistry, Istanbul, Turkey Istanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Cerrahpasa Medical School, Department of Biophysic, Istanbul, TurkeyThe purpose of this research was to investigate the acute effects of Tarantula cubensis extract (Theranekron, 1:100/D2, Richter Pharma, Austria) on some serum enzymes and trace elements, and the cardiovascular system in sheep. Seven sheep (age 6 months, 35±10 kg) were used in this study. Theranekron was applied in 6 ml doses subcutaneously. It was determined that in the serum Urea, Creatinin, ALT, ALP, G-GT, LDH, Ca and P levels were increased and T. protein, Mg, Cu, Fe, Zn and Se levels were decreased. The important results obtained after the treatment with Theranekron on cardiovascular system were blood pressure increases and some morphological changes in ECG. We concluded the Theranekron treatment can cause adverse effects in sheep and further investigation of the efficacy of Theranekron treatment is warranted.http://www.journals.istanbul.edu.tr/iuvfd/article/view/5000079774/5000074145Tarantula cubensis ekstraktıkoyunEKGiz elementler
spellingShingle Remzi GONUL
Lora KOENHEMSİ
Handan AYDIN
Tevfik GULYASAR
Hasret DEMIRCAN YARDIBI
Erman OR
Gulhan HOSTURK
Abdulkadir UYSAL
Bora BARUTCU
Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep
İstanbul Üniversitesi Veteriner Fakültesi Dergisi
Tarantula cubensis ekstraktı
koyun
EKG
iz elementler
title Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep
title_full Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep
title_fullStr Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep
title_full_unstemmed Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep
title_short Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep
title_sort effects of tarantula cubensis extract on electrocardiographic and trace element status in sheep
topic Tarantula cubensis ekstraktı
koyun
EKG
iz elementler
url http://www.journals.istanbul.edu.tr/iuvfd/article/view/5000079774/5000074145
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