Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep
The purpose of this research was to investigate the acute effects of Tarantula cubensis extract (Theranekron, 1:100/D2, Richter Pharma, Austria) on some serum enzymes and trace elements, and the cardiovascular system in sheep. Seven sheep (age 6 months, 35±10 kg) were used in this study. Theranekron...
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Format: | Article |
Language: | English |
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Istanbul University
2015-01-01
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Series: | İstanbul Üniversitesi Veteriner Fakültesi Dergisi |
Subjects: | |
Online Access: | http://www.journals.istanbul.edu.tr/iuvfd/article/view/5000079774/5000074145 |
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author | Remzi GONUL Lora KOENHEMSİ Handan AYDIN Tevfik GULYASAR Hasret DEMIRCAN YARDIBI Erman OR Gulhan HOSTURK Abdulkadir UYSAL Bora BARUTCU |
author_facet | Remzi GONUL Lora KOENHEMSİ Handan AYDIN Tevfik GULYASAR Hasret DEMIRCAN YARDIBI Erman OR Gulhan HOSTURK Abdulkadir UYSAL Bora BARUTCU |
author_sort | Remzi GONUL |
collection | DOAJ |
description | The purpose of this research was to investigate the acute effects of Tarantula cubensis extract (Theranekron, 1:100/D2, Richter Pharma, Austria) on some serum enzymes and trace elements, and the cardiovascular system in sheep. Seven sheep (age 6 months, 35±10 kg) were used in this study. Theranekron was applied in 6 ml doses subcutaneously. It was determined that in the serum Urea, Creatinin, ALT, ALP, G-GT, LDH, Ca and P levels were increased and T. protein, Mg, Cu, Fe, Zn and Se levels were decreased. The important results obtained after the treatment with Theranekron on cardiovascular system were blood pressure increases and some morphological changes in ECG. We concluded the Theranekron treatment can cause adverse effects in sheep and further investigation of the efficacy of Theranekron treatment is warranted. |
first_indexed | 2024-04-10T10:22:20Z |
format | Article |
id | doaj.art-844eef92be854eb48bdfcbf9c213ee71 |
institution | Directory Open Access Journal |
issn | 0250-2836 0250-2836 |
language | English |
last_indexed | 2024-04-10T10:22:20Z |
publishDate | 2015-01-01 |
publisher | Istanbul University |
record_format | Article |
series | İstanbul Üniversitesi Veteriner Fakültesi Dergisi |
spelling | doaj.art-844eef92be854eb48bdfcbf9c213ee712023-02-15T16:21:34ZengIstanbul Universityİstanbul Üniversitesi Veteriner Fakültesi Dergisi0250-28360250-28362015-01-01411798310.16988/iuvfd.2015.25554Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in SheepRemzi GONUL0Lora KOENHEMSİ1 Handan AYDIN2Tevfik GULYASAR3Hasret DEMIRCAN YARDIBI4Erman OR5Gulhan HOSTURK6Abdulkadir UYSAL7Bora BARUTCU8Istanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Istanbul, TurkeyTrakya University, Medical School, Department of Biophysic, Edirne, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Biochemistry, Istanbul, Turkey Istanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Faculty of Veterinary Medicine, Department of Biochemistry, Istanbul, Turkey Istanbul University, Faculty of Veterinary Medicine, Department of Internal Medicine, Istanbul, TurkeyIstanbul University, Cerrahpasa Medical School, Department of Biophysic, Istanbul, TurkeyThe purpose of this research was to investigate the acute effects of Tarantula cubensis extract (Theranekron, 1:100/D2, Richter Pharma, Austria) on some serum enzymes and trace elements, and the cardiovascular system in sheep. Seven sheep (age 6 months, 35±10 kg) were used in this study. Theranekron was applied in 6 ml doses subcutaneously. It was determined that in the serum Urea, Creatinin, ALT, ALP, G-GT, LDH, Ca and P levels were increased and T. protein, Mg, Cu, Fe, Zn and Se levels were decreased. The important results obtained after the treatment with Theranekron on cardiovascular system were blood pressure increases and some morphological changes in ECG. We concluded the Theranekron treatment can cause adverse effects in sheep and further investigation of the efficacy of Theranekron treatment is warranted.http://www.journals.istanbul.edu.tr/iuvfd/article/view/5000079774/5000074145Tarantula cubensis ekstraktıkoyunEKGiz elementler |
spellingShingle | Remzi GONUL Lora KOENHEMSİ Handan AYDIN Tevfik GULYASAR Hasret DEMIRCAN YARDIBI Erman OR Gulhan HOSTURK Abdulkadir UYSAL Bora BARUTCU Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep İstanbul Üniversitesi Veteriner Fakültesi Dergisi Tarantula cubensis ekstraktı koyun EKG iz elementler |
title | Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep |
title_full | Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep |
title_fullStr | Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep |
title_full_unstemmed | Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep |
title_short | Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep |
title_sort | effects of tarantula cubensis extract on electrocardiographic and trace element status in sheep |
topic | Tarantula cubensis ekstraktı koyun EKG iz elementler |
url | http://www.journals.istanbul.edu.tr/iuvfd/article/view/5000079774/5000074145 |
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