Cytotoxic Terpene Quinones from Marine Sponges
The 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities. The cytotoxic and antiproliferative properties of many natural sesquiterpene quinones and hydroquinones from spo...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2010-11-01
|
| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1660-3397/8/12/2849/ |
| _version_ | 1798006812665970688 |
|---|---|
| author | Marina Gordaliza |
| author_facet | Marina Gordaliza |
| author_sort | Marina Gordaliza |
| collection | DOAJ |
| description | The 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities. The cytotoxic and antiproliferative properties of many natural sesquiterpene quinones and hydroquinones from sponges of the order Dictyoceratida, such as avarol, avarone, illimaquinone, nakijiquinone and bolinaquinone, offer promising opportunities for the development of new antitumor agents. The present review summarizes the structure and cytotoxicity of natural terpenequinones/hydroquinones and their bioactive analogues and derivatives. |
| first_indexed | 2024-04-11T13:00:33Z |
| format | Article |
| id | doaj.art-844ffdff12d442ef839635ac0e870212 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T13:00:33Z |
| publishDate | 2010-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-844ffdff12d442ef839635ac0e8702122022-12-22T04:22:57ZengMDPI AGMarine Drugs1660-33972010-11-018122849287010.3390/md8122849Cytotoxic Terpene Quinones from Marine SpongesMarina GordalizaThe 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities. The cytotoxic and antiproliferative properties of many natural sesquiterpene quinones and hydroquinones from sponges of the order Dictyoceratida, such as avarol, avarone, illimaquinone, nakijiquinone and bolinaquinone, offer promising opportunities for the development of new antitumor agents. The present review summarizes the structure and cytotoxicity of natural terpenequinones/hydroquinones and their bioactive analogues and derivatives.http://www.mdpi.com/1660-3397/8/12/2849/terpene quinoneterpene hydroquinoneavaroneavarolcytotoxicity |
| spellingShingle | Marina Gordaliza Cytotoxic Terpene Quinones from Marine Sponges Marine Drugs terpene quinone terpene hydroquinone avarone avarol cytotoxicity |
| title | Cytotoxic Terpene Quinones from Marine Sponges |
| title_full | Cytotoxic Terpene Quinones from Marine Sponges |
| title_fullStr | Cytotoxic Terpene Quinones from Marine Sponges |
| title_full_unstemmed | Cytotoxic Terpene Quinones from Marine Sponges |
| title_short | Cytotoxic Terpene Quinones from Marine Sponges |
| title_sort | cytotoxic terpene quinones from marine sponges |
| topic | terpene quinone terpene hydroquinone avarone avarol cytotoxicity |
| url | http://www.mdpi.com/1660-3397/8/12/2849/ |
| work_keys_str_mv | AT marinagordaliza cytotoxicterpenequinonesfrommarinesponges |