Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia
Metal organic frameworks (MOF) coated with mammalian cell membranes have good biocompatibility. Here, the authors develop a cobalt based hydrogen sulphide producing MOF cloaked with a macrophage membrane and show that the subsequent system can reduce tumour growth in mice.
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32349-2 |
| _version_ | 1818504926662230016 |
|---|---|
| author | Kai Cheng Bo Liu Xiao-Shuai Zhang Ruo-Yun Zhang Fang Zhang Ghazal Ashraf Guo-Qing Fan Ming-Yu Tian Xing Sun Jing Yuan Yuan-Di Zhao |
| author_facet | Kai Cheng Bo Liu Xiao-Shuai Zhang Ruo-Yun Zhang Fang Zhang Ghazal Ashraf Guo-Qing Fan Ming-Yu Tian Xing Sun Jing Yuan Yuan-Di Zhao |
| author_sort | Kai Cheng |
| collection | DOAJ |
| description | Metal organic frameworks (MOF) coated with mammalian cell membranes have good biocompatibility. Here, the authors develop a cobalt based hydrogen sulphide producing MOF cloaked with a macrophage membrane and show that the subsequent system can reduce tumour growth in mice. |
| first_indexed | 2024-12-10T21:43:49Z |
| format | Article |
| id | doaj.art-8450d2a20d884ad78793a09aff80e5ff |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-10T21:43:49Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-8450d2a20d884ad78793a09aff80e5ff2022-12-22T01:32:26ZengNature PortfolioNature Communications2041-17232022-08-0113111810.1038/s41467-022-32349-2Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermiaKai Cheng0Bo Liu1Xiao-Shuai Zhang2Ruo-Yun Zhang3Fang Zhang4Ghazal Ashraf5Guo-Qing Fan6Ming-Yu Tian7Xing Sun8Jing Yuan9Yuan-Di Zhao10Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyMetal organic frameworks (MOF) coated with mammalian cell membranes have good biocompatibility. Here, the authors develop a cobalt based hydrogen sulphide producing MOF cloaked with a macrophage membrane and show that the subsequent system can reduce tumour growth in mice.https://doi.org/10.1038/s41467-022-32349-2 |
| spellingShingle | Kai Cheng Bo Liu Xiao-Shuai Zhang Ruo-Yun Zhang Fang Zhang Ghazal Ashraf Guo-Qing Fan Ming-Yu Tian Xing Sun Jing Yuan Yuan-Di Zhao Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia Nature Communications |
| title | Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia |
| title_full | Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia |
| title_fullStr | Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia |
| title_full_unstemmed | Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia |
| title_short | Biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia |
| title_sort | biomimetic material degradation for synergistic enhanced therapy by regulating endogenous energy metabolism imaging under hypothermia |
| url | https://doi.org/10.1038/s41467-022-32349-2 |
| work_keys_str_mv | AT kaicheng biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT boliu biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT xiaoshuaizhang biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT ruoyunzhang biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT fangzhang biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT ghazalashraf biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT guoqingfan biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT mingyutian biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT xingsun biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT jingyuan biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia AT yuandizhao biomimeticmaterialdegradationforsynergisticenhancedtherapybyregulatingendogenousenergymetabolismimagingunderhypothermia |