Correlation between Gut Microbiota and Lung Cancer
Gene-environment interactions underlie cancer susceptibility and progression. The human body is exposed to and affected by the microenvironment seiscasts of various microorganisms and their metabolites, such as the microenvironment of gut microbiota. The relative abundance of some intestinal microbe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2020-10-01
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| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.39 |
| _version_ | 1828453965627392000 |
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| author | Jun TENG Yanfen ZHAO Yunning JIANG Qi WANG Yongsheng ZHANG |
| author_facet | Jun TENG Yanfen ZHAO Yunning JIANG Qi WANG Yongsheng ZHANG |
| author_sort | Jun TENG |
| collection | DOAJ |
| description | Gene-environment interactions underlie cancer susceptibility and progression. The human body is exposed to and affected by the microenvironment seiscasts of various microorganisms and their metabolites, such as the microenvironment of gut microbiota. The relative abundance of some intestinal microbes in lung cancer patients was significantly different from that in the control group. These studies suggest that gut microbiota may be associated with lung cancer through some ways. At the same time, gut microbiota is relatively manageable environmental variables compared to the external environment we are exposed to, as they are highly quantifiable and relatively stable in the individual. Just as some measures of diagnosis, intervention and treatment of lung cancer targeting gut microbiota have achieved some results in clinical practice. In this review, we mainly discuss the role of gut microbiota and its metabolites in the progression and treatment of lung cancer through certain ways, such as regulation of metabolism, inflammation, and immune response. Finally, based on current research progress, it is inferred that research on gut microbiota may be an effective approach to the precise and personalized medical treatment of lung cancer. |
| first_indexed | 2024-12-11T00:15:22Z |
| format | Article |
| id | doaj.art-8452d7decede4ec9922f0a1d6af3e4af |
| institution | Directory Open Access Journal |
| issn | 1009-3419 1999-6187 |
| language | zho |
| last_indexed | 2024-12-11T00:15:22Z |
| publishDate | 2020-10-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-8452d7decede4ec9922f0a1d6af3e4af2022-12-22T01:27:59ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872020-10-01231090991510.3779/j.issn.1009-3419.2020.101.39Correlation between Gut Microbiota and Lung CancerJun TENG0Yanfen ZHAO1Yunning JIANG2Qi WANG3Yongsheng ZHANG4Graduate School, Beijing University of Chinese Medicine, Beijing 100029, ChinaGraduate School, Beijing University of Chinese Medicine, Beijing 100029, ChinaGraduate School, Beijing University of Chinese Medicine, Beijing 100029, ChinaDepartment of Respiratory, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, ChinaDepartment of Respiratory, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, ChinaGene-environment interactions underlie cancer susceptibility and progression. The human body is exposed to and affected by the microenvironment seiscasts of various microorganisms and their metabolites, such as the microenvironment of gut microbiota. The relative abundance of some intestinal microbes in lung cancer patients was significantly different from that in the control group. These studies suggest that gut microbiota may be associated with lung cancer through some ways. At the same time, gut microbiota is relatively manageable environmental variables compared to the external environment we are exposed to, as they are highly quantifiable and relatively stable in the individual. Just as some measures of diagnosis, intervention and treatment of lung cancer targeting gut microbiota have achieved some results in clinical practice. In this review, we mainly discuss the role of gut microbiota and its metabolites in the progression and treatment of lung cancer through certain ways, such as regulation of metabolism, inflammation, and immune response. Finally, based on current research progress, it is inferred that research on gut microbiota may be an effective approach to the precise and personalized medical treatment of lung cancer.http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.39gut microbiotalung neoplasmsmetabolisminflammationimmune response |
| spellingShingle | Jun TENG Yanfen ZHAO Yunning JIANG Qi WANG Yongsheng ZHANG Correlation between Gut Microbiota and Lung Cancer Chinese Journal of Lung Cancer gut microbiota lung neoplasms metabolism inflammation immune response |
| title | Correlation between Gut Microbiota and Lung Cancer |
| title_full | Correlation between Gut Microbiota and Lung Cancer |
| title_fullStr | Correlation between Gut Microbiota and Lung Cancer |
| title_full_unstemmed | Correlation between Gut Microbiota and Lung Cancer |
| title_short | Correlation between Gut Microbiota and Lung Cancer |
| title_sort | correlation between gut microbiota and lung cancer |
| topic | gut microbiota lung neoplasms metabolism inflammation immune response |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.39 |
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