New Short Term Prediction Method for Chemical Carcinogenicity by Hepatic Transcript Profiling following 28-Day Toxicity Tests in Rats

New Short Term Prediction Method for Chemical Carcinogenicity by Hepatic Transcript Profiling following 28-Day Toxicity Tests in Rats

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We have previously shown the hepatic gene expression profiles of carcinogens in 28-day toxicity tests were clustered into three major groups (Group-1 to 3). Here, we developed a new prediction method for Group-1 carcinogens which consist mainly of genotoxic rat hepatocarcinogens. The prediction form...

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Bibliographic Details
Main Authors: Hiroshi Matsumoto, Yoshikuni Yakabe, Fumiyo Saito, Koichi Saito, Kayo Sumida, Masaru Sekijima, Koji Nakayama, Hideki Miyaura, Masanori Otsuka, Tomoyuki Shirai
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S7789

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