Genetic Alterations in Childhood Acute Lymphoblastic Leukemia: Interactions with Clinical Features and Treatment Response

Genetic Alterations in Childhood Acute Lymphoblastic Leukemia: Interactions with Clinical Features and Treatment Response

Acute lymphoblastic leukemia (ALL) is the most common cancer among children. This aggressive cancer comprises multiple molecular subtypes, each harboring a distinct constellation of somatic, and to a lesser extent, inherited genetic alterations. With recent advances in genomic analyses such as next-...

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Bibliographic Details
Main Authors: Shawn H. R. Lee, Zhenhua Li, Si Ting Tai, Bernice L. Z. Oh, Allen E. J. Yeoh
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
childhood acute lymphoblastic leukemia
genetic subtypes
RNA-Seq
NCI criteria
MRD
<i>IKZF1<sup>del</sup></i>
Online Access:https://www.mdpi.com/2072-6694/13/16/4068

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https://www.mdpi.com/2072-6694/13/16/4068

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