Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocomposites
Summary: The detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA) is crucial for understanding and managing various illnesses. In this research, Pt@g-C3N4 nanoparticles were synthesized via hydrothermal method and combined with N-doped carbon nanotubes (N-CNTs). The Pt@g-C3N4/N-CNTs-mo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224004620 |
| _version_ | 1797292904142602240 |
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| author | Lin Zhang Liu Yu Junyang Peng Xiaoying Hou Hongzhi Du |
| author_facet | Lin Zhang Liu Yu Junyang Peng Xiaoying Hou Hongzhi Du |
| author_sort | Lin Zhang |
| collection | DOAJ |
| description | Summary: The detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA) is crucial for understanding and managing various illnesses. In this research, Pt@g-C3N4 nanoparticles were synthesized via hydrothermal method and combined with N-doped carbon nanotubes (N-CNTs). The Pt@g-C3N4/N-CNTs-modified glassy carbon (GC) electrode was fabricated as an electrochemical sensor for the determination of AA, DA, and UA. The linear response range of AA, DA, and UA in the optimal condition was 100–3,000 μM, 1–100 μM, and 2–215 μM boasting a low detection limit (S/N = 3) of 29.44 μM (AA), 0.21 μM (UA), and 2.99 μM (DA), respectively. Additionally, the recoveries of AA, DA, and UA in serum sample were 100.4%–106.7%. These results corroborate the feasibility of the proposed method for the simultaneous, sensitive, and reliable detection of AA, DA, and UA. Our Pt@g-C3N4/N-CNTs/GC electrode can provide a potential strategy for disease diagnosis and health monitoring in clinical settings. |
| first_indexed | 2024-03-07T20:04:13Z |
| format | Article |
| id | doaj.art-8459799d30894e539e68ab891a3e3d24 |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-03-07T20:04:13Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-8459799d30894e539e68ab891a3e3d242024-02-28T05:13:59ZengElsevieriScience2589-00422024-03-01273109241Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocompositesLin Zhang0Liu Yu1Junyang Peng2Xiaoying Hou3Hongzhi Du4School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Wuhan 430065, China; Corresponding authorSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, ChinaSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, ChinaSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Cancer Institute, School of Medicine, Jianghan University, Wuhan, China; Corresponding authorSchool of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Wuhan 430065, China; Corresponding authorSummary: The detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA) is crucial for understanding and managing various illnesses. In this research, Pt@g-C3N4 nanoparticles were synthesized via hydrothermal method and combined with N-doped carbon nanotubes (N-CNTs). The Pt@g-C3N4/N-CNTs-modified glassy carbon (GC) electrode was fabricated as an electrochemical sensor for the determination of AA, DA, and UA. The linear response range of AA, DA, and UA in the optimal condition was 100–3,000 μM, 1–100 μM, and 2–215 μM boasting a low detection limit (S/N = 3) of 29.44 μM (AA), 0.21 μM (UA), and 2.99 μM (DA), respectively. Additionally, the recoveries of AA, DA, and UA in serum sample were 100.4%–106.7%. These results corroborate the feasibility of the proposed method for the simultaneous, sensitive, and reliable detection of AA, DA, and UA. Our Pt@g-C3N4/N-CNTs/GC electrode can provide a potential strategy for disease diagnosis and health monitoring in clinical settings.http://www.sciencedirect.com/science/article/pii/S2589004224004620SensorElectrochemistryApplied sciencesNanomaterials |
| spellingShingle | Lin Zhang Liu Yu Junyang Peng Xiaoying Hou Hongzhi Du Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocomposites iScience Sensor Electrochemistry Applied sciences Nanomaterials |
| title | Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocomposites |
| title_full | Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocomposites |
| title_fullStr | Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocomposites |
| title_full_unstemmed | Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocomposites |
| title_short | Highly sensitive and simultaneous detection of ascorbic acid, dopamine, and uric acid using Pt@g-C3N4/N-CNTs nanocomposites |
| title_sort | highly sensitive and simultaneous detection of ascorbic acid dopamine and uric acid using pt g c3n4 n cnts nanocomposites |
| topic | Sensor Electrochemistry Applied sciences Nanomaterials |
| url | http://www.sciencedirect.com/science/article/pii/S2589004224004620 |
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