Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future Applications
In recent years, plant-derived extracellular vesicles (PDEVs) have gained the interest of many experts in fields such as microbiology and immunology, and research in this field has exponentially increased. These nano-sized particles have provided researchers with a number of interesting findings, ma...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Membranes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0375/11/6/411 |
| _version_ | 1797532064322420736 |
|---|---|
| author | Nader Kameli Anya Dragojlovic-Kerkache Paul Savelkoul Frank R. Stassen |
| author_facet | Nader Kameli Anya Dragojlovic-Kerkache Paul Savelkoul Frank R. Stassen |
| author_sort | Nader Kameli |
| collection | DOAJ |
| description | In recent years, plant-derived extracellular vesicles (PDEVs) have gained the interest of many experts in fields such as microbiology and immunology, and research in this field has exponentially increased. These nano-sized particles have provided researchers with a number of interesting findings, making their application in human health and disease very promising. Both in vitro and in vivo experiments have shown that PDEVs can exhibit a multitude of effects, suggesting that these vesicles may have many potential future applications, including therapeutics and nano-delivery of compounds. While the preliminary results are promising, there are still some challenges to face, such as a lack of protocol standardization, as well as knowledge gaps that need to be filled. This review aims to discuss various aspects of PDEV knowledge, including their preliminary findings, challenges, and future uses, giving insight into the complexity of conducting research in this field. |
| first_indexed | 2024-03-10T10:53:45Z |
| format | Article |
| id | doaj.art-845ae3ddddec4535bdbb2562949ded3f |
| institution | Directory Open Access Journal |
| issn | 2077-0375 |
| language | English |
| last_indexed | 2024-03-10T10:53:45Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Membranes |
| spelling | doaj.art-845ae3ddddec4535bdbb2562949ded3f2023-11-21T22:03:19ZengMDPI AGMembranes2077-03752021-05-0111641110.3390/membranes11060411Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future ApplicationsNader Kameli0Anya Dragojlovic-Kerkache1Paul Savelkoul2Frank R. Stassen3Department of Medical Microbiology, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Center, 6200MD Maastricht, The NetherlandsDepartment of Medical Microbiology, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Center, 6200MD Maastricht, The NetherlandsDepartment of Medical Microbiology, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Center, 6200MD Maastricht, The NetherlandsDepartment of Medical Microbiology, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Center, 6200MD Maastricht, The NetherlandsIn recent years, plant-derived extracellular vesicles (PDEVs) have gained the interest of many experts in fields such as microbiology and immunology, and research in this field has exponentially increased. These nano-sized particles have provided researchers with a number of interesting findings, making their application in human health and disease very promising. Both in vitro and in vivo experiments have shown that PDEVs can exhibit a multitude of effects, suggesting that these vesicles may have many potential future applications, including therapeutics and nano-delivery of compounds. While the preliminary results are promising, there are still some challenges to face, such as a lack of protocol standardization, as well as knowledge gaps that need to be filled. This review aims to discuss various aspects of PDEV knowledge, including their preliminary findings, challenges, and future uses, giving insight into the complexity of conducting research in this field.https://www.mdpi.com/2077-0375/11/6/411extracellular vesiclesplant EVsintestinal homeostasisimmunomodulatory effectstherapeutic applications |
| spellingShingle | Nader Kameli Anya Dragojlovic-Kerkache Paul Savelkoul Frank R. Stassen Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future Applications Membranes extracellular vesicles plant EVs intestinal homeostasis immunomodulatory effects therapeutic applications |
| title | Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future Applications |
| title_full | Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future Applications |
| title_fullStr | Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future Applications |
| title_full_unstemmed | Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future Applications |
| title_short | Plant-Derived Extracellular Vesicles: Current Findings, Challenges, and Future Applications |
| title_sort | plant derived extracellular vesicles current findings challenges and future applications |
| topic | extracellular vesicles plant EVs intestinal homeostasis immunomodulatory effects therapeutic applications |
| url | https://www.mdpi.com/2077-0375/11/6/411 |
| work_keys_str_mv | AT naderkameli plantderivedextracellularvesiclescurrentfindingschallengesandfutureapplications AT anyadragojlovickerkache plantderivedextracellularvesiclescurrentfindingschallengesandfutureapplications AT paulsavelkoul plantderivedextracellularvesiclescurrentfindingschallengesandfutureapplications AT frankrstassen plantderivedextracellularvesiclescurrentfindingschallengesandfutureapplications |