Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved]
During the past decade, it became clear that the electric field elicited by non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are substantially influenced by variations in individual head and brain anat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2018-11-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/7-704/v2 |
| _version_ | 1819172792448319488 |
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| author | Nya Mehnwolo Boayue Gábor Csifcsák Oula Puonti Axel Thielscher Matthias Mittner |
| author_facet | Nya Mehnwolo Boayue Gábor Csifcsák Oula Puonti Axel Thielscher Matthias Mittner |
| author_sort | Nya Mehnwolo Boayue |
| collection | DOAJ |
| description | During the past decade, it became clear that the electric field elicited by non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are substantially influenced by variations in individual head and brain anatomy. In addition to structural variations in the healthy, several psychiatric disorders are characterized by anatomical alterations that are likely to further constrain the intracerebral effects of NIBS. Here, we present high-resolution realistic head models derived from structural magnetic resonance imaging data of 19 healthy adults and 19 patients diagnosed with major depressive disorder (MDD). By using a freely available software package for modelling the electric fields induced by different NIBS protocols, we show that our head models are well-suited for assessing inter-individual and between-group variability in the magnitude and focality of tDCS-induced electric fields for two protocols targeting the left dorsolateral prefrontal cortex. |
| first_indexed | 2024-12-22T20:12:49Z |
| format | Article |
| id | doaj.art-845c8144a14a42379bb1f9848020ad16 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-22T20:12:49Z |
| publishDate | 2018-11-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-845c8144a14a42379bb1f9848020ad162022-12-21T18:14:02ZengF1000 Research LtdF1000Research2046-14022018-11-01710.12688/f1000research.15125.218435Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved]Nya Mehnwolo Boayue0Gábor Csifcsák1Oula Puonti2Axel Thielscher3Matthias Mittner4Department of Psychology, Faculty of Health Sciences, University of Tromsø - The Arctic University of Norway, Tromsø, 9037, NorwayDepartment of Psychology, Faculty of Health Sciences, University of Tromsø - The Arctic University of Norway, Tromsø, 9037, NorwayCenter for Magnetic Resonance, Department of Electrical Engineering, Technical University of Denmark, Kongens Lyngby, 2800, DenmarkCenter for Magnetic Resonance, Department of Electrical Engineering, Technical University of Denmark, Kongens Lyngby, 2800, DenmarkDepartment of Psychology, Faculty of Health Sciences, University of Tromsø - The Arctic University of Norway, Tromsø, 9037, NorwayDuring the past decade, it became clear that the electric field elicited by non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are substantially influenced by variations in individual head and brain anatomy. In addition to structural variations in the healthy, several psychiatric disorders are characterized by anatomical alterations that are likely to further constrain the intracerebral effects of NIBS. Here, we present high-resolution realistic head models derived from structural magnetic resonance imaging data of 19 healthy adults and 19 patients diagnosed with major depressive disorder (MDD). By using a freely available software package for modelling the electric fields induced by different NIBS protocols, we show that our head models are well-suited for assessing inter-individual and between-group variability in the magnitude and focality of tDCS-induced electric fields for two protocols targeting the left dorsolateral prefrontal cortex.https://f1000research.com/articles/7-704/v2 |
| spellingShingle | Nya Mehnwolo Boayue Gábor Csifcsák Oula Puonti Axel Thielscher Matthias Mittner Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved] F1000Research |
| title | Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved] |
| title_full | Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved] |
| title_fullStr | Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved] |
| title_full_unstemmed | Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved] |
| title_short | Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation [version 2; referees: 2 approved] |
| title_sort | head models of healthy and depressed adults for simulating the electric fields of non invasive electric brain stimulation version 2 referees 2 approved |
| url | https://f1000research.com/articles/7-704/v2 |
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