Carbene-catalyzed atroposelective synthesis of axially chiral styrenes
Axially chiral styrenes bearing a chiral axis between a sterically non-congested acyclic alkene and an aryl ring are difficult to prepare due to low rotational barrier of the axis. Here the authors present a method to form axially chiral styrenes bearing sulfones and carboxylic acids via NHC catalys...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-27771-x |
| _version_ | 1818753853592436736 |
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| author | Jia-Lei Yan Rakesh Maiti Shi-Chao Ren Weiyi Tian Tingting Li Jun Xu Bivas Mondal Zhichao Jin Yonggui Robin Chi |
| author_facet | Jia-Lei Yan Rakesh Maiti Shi-Chao Ren Weiyi Tian Tingting Li Jun Xu Bivas Mondal Zhichao Jin Yonggui Robin Chi |
| author_sort | Jia-Lei Yan |
| collection | DOAJ |
| description | Axially chiral styrenes bearing a chiral axis between a sterically non-congested acyclic alkene and an aryl ring are difficult to prepare due to low rotational barrier of the axis. Here the authors present a method to form axially chiral styrenes bearing sulfones and carboxylic acids via NHC catalysis. |
| first_indexed | 2024-12-18T05:13:58Z |
| format | Article |
| id | doaj.art-8462cbeb379e4e70b3741d417ad89392 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T05:13:58Z |
| publishDate | 2022-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-8462cbeb379e4e70b3741d417ad893922022-12-21T21:19:49ZengNature PortfolioNature Communications2041-17232022-01-011311810.1038/s41467-021-27771-xCarbene-catalyzed atroposelective synthesis of axially chiral styrenesJia-Lei Yan0Rakesh Maiti1Shi-Chao Ren2Weiyi Tian3Tingting Li4Jun Xu5Bivas Mondal6Zhichao Jin7Yonggui Robin Chi8Division of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological UniversityDivision of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological UniversityDivision of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological UniversityGuizhou University of Traditional Chinese MedicineLaboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi DistrictDivision of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological UniversityDivision of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological UniversityLaboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi DistrictDivision of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological UniversityAxially chiral styrenes bearing a chiral axis between a sterically non-congested acyclic alkene and an aryl ring are difficult to prepare due to low rotational barrier of the axis. Here the authors present a method to form axially chiral styrenes bearing sulfones and carboxylic acids via NHC catalysis.https://doi.org/10.1038/s41467-021-27771-x |
| spellingShingle | Jia-Lei Yan Rakesh Maiti Shi-Chao Ren Weiyi Tian Tingting Li Jun Xu Bivas Mondal Zhichao Jin Yonggui Robin Chi Carbene-catalyzed atroposelective synthesis of axially chiral styrenes Nature Communications |
| title | Carbene-catalyzed atroposelective synthesis of axially chiral styrenes |
| title_full | Carbene-catalyzed atroposelective synthesis of axially chiral styrenes |
| title_fullStr | Carbene-catalyzed atroposelective synthesis of axially chiral styrenes |
| title_full_unstemmed | Carbene-catalyzed atroposelective synthesis of axially chiral styrenes |
| title_short | Carbene-catalyzed atroposelective synthesis of axially chiral styrenes |
| title_sort | carbene catalyzed atroposelective synthesis of axially chiral styrenes |
| url | https://doi.org/10.1038/s41467-021-27771-x |
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