A case of sporadic Creutzfeldt-Jakob disease
Sporadic Creutzfeldt-Jakob disease (CJD) is a very rare and fatal disease caused by prions – proteins with unique characteristics and infective potential. The typical clinical presentation is of a rapidly progressive dementia with myoclonus, cerebellar, pyramidal, extra pyramidal and visual signs. T...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2012-06-01
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| Series: | Romanian Journal of Neurology |
| Subjects: | |
| Online Access: | https://rjn.com.ro/articles/2012.2/RJN_2012_2_Art-05.pdf |
| Summary: | Sporadic Creutzfeldt-Jakob disease (CJD) is a very rare and fatal disease caused by prions – proteins with unique characteristics and infective potential. The typical clinical presentation is of a rapidly progressive dementia with myoclonus, cerebellar, pyramidal, extra pyramidal and visual signs. The definitive diagnosis is histological, but in the context of suggestive symptoms, EEG, MRI and 14-3-3 protein in the CSF can be very helpful. We present the case of a 47 year old female patient with rapid onset cognitive decline and myoclonus of the right arm, along with typical paraclinical findings. |
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| ISSN: | 1843-8148 2069-6094 |