Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes
Oocyte meiosis must achieve spindle bipolarization without predefined spatial cues. Yoshida et al. demonstrate that spindle bipolarization during meiosis I in mouse oocytes requires kinetochores to prevent chromosome segregation errors, a phenomenon that does not occur in error-prone human oocytes.
Bibliographic Details
| Main Authors: |
Shuhei Yoshida,
Sui Nishiyama,
Lisa Lister,
Shu Hashimoto,
Tappei Mishina,
Aurélien Courtois,
Hirohisa Kyogoku,
Takaya Abe,
Aki Shiraishi,
Meenakshi Choudhary,
Yoshiharu Nakaoka,
Mary Herbert,
Tomoya S. Kitajima |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-16488-y
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