Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor Operation
Background Excessive requests for preoperative packed red cell (PRC) preparation have been noted, resulting in waste of blood products and higher costs in brain tumor surgery. The objectives of the present study were as follows: (1) the primary objective was to assess the effectiveness index of bloo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2023-04-01
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| Series: | Indian Journal of Neurosurgery |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768066 |
| _version_ | 1797851515726069760 |
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| author | Thara Tunthanathip Sakchai Sae-heng Thakul Oearsakul Anukoon Kaewborisutsakul Chin Taweesomboonyat |
| author_facet | Thara Tunthanathip Sakchai Sae-heng Thakul Oearsakul Anukoon Kaewborisutsakul Chin Taweesomboonyat |
| author_sort | Thara Tunthanathip |
| collection | DOAJ |
| description | Background Excessive requests for preoperative packed red cell (PRC) preparation have been noted, resulting in waste of blood products and higher costs in brain tumor surgery. The objectives of the present study were as follows: (1) the primary objective was to assess the effectiveness index of blood preparation and utilization; (2) the secondary objective was to explore factors associated with intraoperative PRC transfusion; and (3) the third objective was to identify the prevalence and analyze risk factors of massive transfusion.
Methods A retrospective cohort study was done on patients who had undergone brain tumor operations. The effectiveness indexes of preoperative PRC preparation and intraoperative utilization were calculated as follows: the crossmatch to transfusion (C/T) ratio, transfusion probability (Tp), and transfusion index (Ti). Additionally, factors associated with intraoperative PRC transfusion and massive transfusion were analyzed.
Results There were 1,708 brain tumor patients and overall C/T, Tp, and Ti were 3.27, 45.54%, and 1.10, respectively. Prevalence of intraoperative PRC transfusion was 44.8%, and meningioma, intraosseous/skull-based tumor, and tumor size were linked with massive transfusion.
Conclusion Unnecessary preoperative blood component preparation for brain tumor surgery was noticed in routine practice. Exploring intraoperative transfusion variables has been challenged in optimizing crossmatch and actual use. |
| first_indexed | 2024-04-09T19:18:02Z |
| format | Article |
| id | doaj.art-846d370933504e48817b2833f0dac0f2 |
| institution | Directory Open Access Journal |
| issn | 2277-954X 2277-9167 |
| language | English |
| last_indexed | 2024-04-09T19:18:02Z |
| publishDate | 2023-04-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Indian Journal of Neurosurgery |
| spelling | doaj.art-846d370933504e48817b2833f0dac0f22023-04-05T23:03:28ZengThieme Medical Publishers, Inc.Indian Journal of Neurosurgery2277-954X2277-91672023-04-0110.1055/s-0043-1768066Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor OperationThara Tunthanathip0Sakchai Sae-heng1Thakul Oearsakul2Anukoon Kaewborisutsakul3Chin Taweesomboonyat4Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, ThailandDivision of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, ThailandDivision of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, ThailandDivision of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, ThailandDivision of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, ThailandBackground Excessive requests for preoperative packed red cell (PRC) preparation have been noted, resulting in waste of blood products and higher costs in brain tumor surgery. The objectives of the present study were as follows: (1) the primary objective was to assess the effectiveness index of blood preparation and utilization; (2) the secondary objective was to explore factors associated with intraoperative PRC transfusion; and (3) the third objective was to identify the prevalence and analyze risk factors of massive transfusion. Methods A retrospective cohort study was done on patients who had undergone brain tumor operations. The effectiveness indexes of preoperative PRC preparation and intraoperative utilization were calculated as follows: the crossmatch to transfusion (C/T) ratio, transfusion probability (Tp), and transfusion index (Ti). Additionally, factors associated with intraoperative PRC transfusion and massive transfusion were analyzed. Results There were 1,708 brain tumor patients and overall C/T, Tp, and Ti were 3.27, 45.54%, and 1.10, respectively. Prevalence of intraoperative PRC transfusion was 44.8%, and meningioma, intraosseous/skull-based tumor, and tumor size were linked with massive transfusion. Conclusion Unnecessary preoperative blood component preparation for brain tumor surgery was noticed in routine practice. Exploring intraoperative transfusion variables has been challenged in optimizing crossmatch and actual use.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768066massive transfusionintraoperative transfusionsbrain tumorblood transfusion |
| spellingShingle | Thara Tunthanathip Sakchai Sae-heng Thakul Oearsakul Anukoon Kaewborisutsakul Chin Taweesomboonyat Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor Operation Indian Journal of Neurosurgery massive transfusion intraoperative transfusions brain tumor blood transfusion |
| title | Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor Operation |
| title_full | Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor Operation |
| title_fullStr | Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor Operation |
| title_full_unstemmed | Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor Operation |
| title_short | Effectiveness of Preoperative Red Cell Preparation and Intraoperative Massive Transfusion in Brain Tumor Operation |
| title_sort | effectiveness of preoperative red cell preparation and intraoperative massive transfusion in brain tumor operation |
| topic | massive transfusion intraoperative transfusions brain tumor blood transfusion |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768066 |
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