Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic Acid
Polyphenol, characterized by various phenolic rings in the chemical structure and an abundance in nature, can be extracted from vegetables, grains, chocolates, fruits, tea, legumes, and seeds, among other sources. Tannic acid (TA), a classical polyphenol with a specific chemical structure, has been...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-10-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fchem.2020.583484/full |
| _version_ | 1811207119767076864 |
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| author | Ruofei Lu Ruofei Lu Xiaoqiang Zhang Xiaoqiang Zhang Xinxiu Cheng Xinxiu Cheng Yagang Zhang Yagang Zhang Yagang Zhang Yagang Zhang Xingjie Zan Letao Zhang |
| author_facet | Ruofei Lu Ruofei Lu Xiaoqiang Zhang Xiaoqiang Zhang Xinxiu Cheng Xinxiu Cheng Yagang Zhang Yagang Zhang Yagang Zhang Yagang Zhang Xingjie Zan Letao Zhang |
| author_sort | Ruofei Lu |
| collection | DOAJ |
| description | Polyphenol, characterized by various phenolic rings in the chemical structure and an abundance in nature, can be extracted from vegetables, grains, chocolates, fruits, tea, legumes, and seeds, among other sources. Tannic acid (TA), a classical polyphenol with a specific chemical structure, has been widely used in biomedicine because of its outstanding biocompatibility and antibacterial and antioxidant properties. TA has tunable interactions with various materials that are widely distributed in the body, such as proteins, polysaccharides, and glycoproteins, through multimodes including hydrogen bonding, hydrophobic interactions, and charge interactions, assisting TA as important building blocks in the supramolecular self-assembled materials. This review summarizes the recent immense progress in supramolecular self-assembled materials using TA as building blocks to generate different materials such as hydrogels, nanoparticles/microparticles, hollow capsules, and coating films, with enormous potential medical applications including drug delivery, tumor diagnosis and treatment, bone tissue engineering, biofunctional membrane material, and the treatment of certain diseases. Furthermore, we discuss the challenges and developmental prospects of supramolecular self-assembly nanomaterials based on TA. |
| first_indexed | 2024-04-12T03:58:25Z |
| format | Article |
| id | doaj.art-846e69ba7ddb490a995106a1144cf5e4 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-12T03:58:25Z |
| publishDate | 2020-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-846e69ba7ddb490a995106a1144cf5e42022-12-22T03:48:46ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462020-10-01810.3389/fchem.2020.583484583484Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic AcidRuofei Lu0Ruofei Lu1Xiaoqiang Zhang2Xiaoqiang Zhang3Xinxiu Cheng4Xinxiu Cheng5Yagang Zhang6Yagang Zhang7Yagang Zhang8Yagang Zhang9Xingjie Zan10Letao Zhang11Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, ChinaUniversity of Chinese Academy of Sciences, Beijing, ChinaXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, ChinaUniversity of Chinese Academy of Sciences, Beijing, ChinaXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, ChinaUniversity of Chinese Academy of Sciences, Beijing, ChinaXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, ChinaUniversity of Chinese Academy of Sciences, Beijing, ChinaDepartment of Chemical and Environmental Engineering, Xinjiang Institute of Engineering, Urumqi, ChinaSchool of Materials and Energy, University of Electronic Science and Technology of China, Chengdu, ChinaXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, ChinaXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, ChinaPolyphenol, characterized by various phenolic rings in the chemical structure and an abundance in nature, can be extracted from vegetables, grains, chocolates, fruits, tea, legumes, and seeds, among other sources. Tannic acid (TA), a classical polyphenol with a specific chemical structure, has been widely used in biomedicine because of its outstanding biocompatibility and antibacterial and antioxidant properties. TA has tunable interactions with various materials that are widely distributed in the body, such as proteins, polysaccharides, and glycoproteins, through multimodes including hydrogen bonding, hydrophobic interactions, and charge interactions, assisting TA as important building blocks in the supramolecular self-assembled materials. This review summarizes the recent immense progress in supramolecular self-assembled materials using TA as building blocks to generate different materials such as hydrogels, nanoparticles/microparticles, hollow capsules, and coating films, with enormous potential medical applications including drug delivery, tumor diagnosis and treatment, bone tissue engineering, biofunctional membrane material, and the treatment of certain diseases. Furthermore, we discuss the challenges and developmental prospects of supramolecular self-assembly nanomaterials based on TA.https://www.frontiersin.org/article/10.3389/fchem.2020.583484/fullpolyphenoltannic acidsupramolecularself-assembledmedical applications |
| spellingShingle | Ruofei Lu Ruofei Lu Xiaoqiang Zhang Xiaoqiang Zhang Xinxiu Cheng Xinxiu Cheng Yagang Zhang Yagang Zhang Yagang Zhang Yagang Zhang Xingjie Zan Letao Zhang Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic Acid Frontiers in Chemistry polyphenol tannic acid supramolecular self-assembled medical applications |
| title | Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic Acid |
| title_full | Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic Acid |
| title_fullStr | Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic Acid |
| title_full_unstemmed | Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic Acid |
| title_short | Medical Applications Based on Supramolecular Self-Assembled Materials From Tannic Acid |
| title_sort | medical applications based on supramolecular self assembled materials from tannic acid |
| topic | polyphenol tannic acid supramolecular self-assembled medical applications |
| url | https://www.frontiersin.org/article/10.3389/fchem.2020.583484/full |
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