The flavonoid hesperidin methyl chalcone as a potential therapeutic agent for cancer therapy: Molecular docking, in vitro cytotoxicity, and in vivo antitumor activity

The flavonoid hesperidin methyl chalcone as a potential therapeutic agent for cancer therapy: Molecular docking, in vitro cytotoxicity, and in vivo antitumor activity

Hesperidin methyl chalcone (HMC) is a methylation product of the flavanone hesperidin, a flavonoid derived from citrus fruits. Many reports have emphasized the analgesic, anti-inflammatory and antioxidant properties of HMC. However, the anticancer potential of HMC has not been fully elucidated. The...

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Bibliographic Details
Main Authors: Syed M.D. Rizvi, Manjunatha P. Mudagal, Sateesha S. Boregowda, Talib Hussain, Turki Al Hagbani, Marwa H. Abdallah, El-Sayed Khafagy, Arshad Hussain, Fahad A. Yousif Adam, Amr S. Abu Lila
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Arabian Journal of Chemistry
Subjects:
Cancer
Ehrlich ascites carcinoma
Flavonoid
Hesperidin methyl chalcone
Molecular docking
MTT assay
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223002319

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