NR2F2 alleviates pulmonary fibrosis by inhibition of epithelial cell senescence

NR2F2 alleviates pulmonary fibrosis by inhibition of epithelial cell senescence

Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fatal, and aging-associated interstitial lung disease with a poor prognosis and limited treatment options, while the pathogenesis remains elusive. In this study, we found that the expression of nuclear receptor subfamily 2 group...

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Bibliographic Details
Main Authors: Ruyan Wan, Siqi Long, Shuaichen Ma, Peishuo Yan, Zhongzheng Li, Kai Xu, Hui Lian, Wenwen Li, Yudi Duan, Miaomiao Zhu, Lan Wang, Guoying Yu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Respiratory Research
Subjects:
NR2F2
Cell senescence
DNA damage
Epithelial-mesenchymal crosstalk
Pulmonary fibrosis
Online Access:https://doi.org/10.1186/s12931-024-02777-3

Internet

https://doi.org/10.1186/s12931-024-02777-3

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